Posters
Presentation Type
Poster
Discipline Track
Clinical Science
Abstract Type
Case Report
Abstract
Abstract: Syncope as defined by ACC/AHA is defined as a symptom that presents with an abrupt, transient, complete loss of consciousness, associated with inability to maintain postural tone, with rapid and spontaneous recovery without clinical features of other non-syncope causes of loss of consciousness, such as seizure, antecedent head trauma, or apparent loss of consciousness. Syncope is a common complaint treated in the emergency department and a major reason for hospital admissions. Identification of the etiology of syncope is important for diagnostic and therapeutic purposes. Syncope is a symptom as a presentation with multiple differential diagnosis listed and clearly explained by ACC/AHA. A rare etiology to this common symptom is Waldenstrom macroglobulinemia. Waldenström macroglobulinemia is a rare and currently incurable neoplasm of IgM-expressing B-lymphocytes that is characterized by the occurrence of a monoclonal IgM paraprotein in blood serum and the infiltration of the hematopoietic bone marrow with malignant lymphoplasmacytic cells. Common symptoms are fatigue, unexplained weight loss, nose bleeding, peripheral neuropathy, infections, and change vision. Neurologic manifestations of WM include visual or auditory disturbances, headache, confusion, dizziness, vertigo, stroke and rarely, syncope. We present a patient with multiple comorbidities who was presented to the emergency department after multiple episodes of syncope ultimately diagnosed with Waldenstrom macroglobulinemia.
Academic/Professional Position
Resident
Recommended Citation
Garcia Cruz, Jian; Perez Rodriguez, Julio; Kondapavuluru, Roy Subash; and Cho, Eunbee, "Syncope as a presentation of Waldenstrom Macroglobulinemia" (2024). Research Symposium. 21.
https://scholarworks.utrgv.edu/somrs/2023/posters/21
Included in
Syncope as a presentation of Waldenstrom Macroglobulinemia
Abstract: Syncope as defined by ACC/AHA is defined as a symptom that presents with an abrupt, transient, complete loss of consciousness, associated with inability to maintain postural tone, with rapid and spontaneous recovery without clinical features of other non-syncope causes of loss of consciousness, such as seizure, antecedent head trauma, or apparent loss of consciousness. Syncope is a common complaint treated in the emergency department and a major reason for hospital admissions. Identification of the etiology of syncope is important for diagnostic and therapeutic purposes. Syncope is a symptom as a presentation with multiple differential diagnosis listed and clearly explained by ACC/AHA. A rare etiology to this common symptom is Waldenstrom macroglobulinemia. Waldenström macroglobulinemia is a rare and currently incurable neoplasm of IgM-expressing B-lymphocytes that is characterized by the occurrence of a monoclonal IgM paraprotein in blood serum and the infiltration of the hematopoietic bone marrow with malignant lymphoplasmacytic cells. Common symptoms are fatigue, unexplained weight loss, nose bleeding, peripheral neuropathy, infections, and change vision. Neurologic manifestations of WM include visual or auditory disturbances, headache, confusion, dizziness, vertigo, stroke and rarely, syncope. We present a patient with multiple comorbidities who was presented to the emergency department after multiple episodes of syncope ultimately diagnosed with Waldenstrom macroglobulinemia.