Presentation Type
Poster
Discipline Track
Clinical Science
Abstract Type
Research/Clinical
Abstract
Background: Neurosurgical excision of brain tumors is still regarded as the first line treatment for multiple neoplasms, including meningiomas, gliomas, and metastatic tumors. Advances in technology have allowed neurosurgeons to utilize various approaches that significantly reduce mortality and surgical morbidity. However, the high risk of neurological deficit and tumor recurrence remains. Here, we analyze three neurosurgical approaches: craniotomy, microsurgery with tubular retraction, and tumor ablation. While craniotomy remains as the first line treatment for most brain tumors, we hypothesize that microsurgery and ablation will show greater success of tumor removal with fewer complications.
Methods: Published literature was reviewed from PubMed using search terms “neurosurgical techniques,” “brain neoplasm,” “tubular retractor,” “craniotomy,” “stereotactic radiosurgery,” or “ablation” in varying combinations with boolean commands. Only papers that provided relevant data on extent of resection (EOR) and perioperative or postoperative neurological complications were included. Articles were not screened for identification of brain tumor or patient demographics.
Results: Ten articles that complied with the inclusion criteria were incorporated in the literary review. Craniotomy resulted in an EOR average of >77% across all studies, with a complication average of84% and a75% and
Conclusion: Brain neoplasms portray a significant challenge for neurosurgeons because of the brain’s variety of tumor etiologies, location, and extreme sensitivity; these reasons prohibit a singular method to be established. Tumor ablation, when compared to craniotomy and microsurgery with tubular retractors, demonstrated the highest rate of EOR with the least resulting neurological deficits or surgical complications. Craniotomy and microsurgery had comparable EOR, but craniotomy had a higher percentage of morbidities. It is important to note that multiple strategies for craniotomy are performed and there are several modalities of tumor ablation technology, creating a challenge in accurately comparing each approach. It is also worth mentioning that in all cases, the rate of morbidity and mortality correlated to the tumor’s size, location, and etiology (i.e., primary tumor vs. metastasis), and the patient’s age.
Academic/Professional Position
Medical Student
Mentor/PI Department
Neuroscience
Recommended Citation
Garcia Valdez, Kevin A.; Bhatia, Sonya; Bell, Natasha; Murambadoro, Anesu Karen; Elizondo, Victoria; Cisneros, Fernando; Punch, Kory; and Francis, Alan N., "Modern Neurosurgical Techniques for Surgical Excision of Neoplasms" (2024). Research Symposium. 49.
https://scholarworks.utrgv.edu/somrs/2024/posters/49
Included in
Modern Neurosurgical Techniques for Surgical Excision of Neoplasms
Background: Neurosurgical excision of brain tumors is still regarded as the first line treatment for multiple neoplasms, including meningiomas, gliomas, and metastatic tumors. Advances in technology have allowed neurosurgeons to utilize various approaches that significantly reduce mortality and surgical morbidity. However, the high risk of neurological deficit and tumor recurrence remains. Here, we analyze three neurosurgical approaches: craniotomy, microsurgery with tubular retraction, and tumor ablation. While craniotomy remains as the first line treatment for most brain tumors, we hypothesize that microsurgery and ablation will show greater success of tumor removal with fewer complications.
Methods: Published literature was reviewed from PubMed using search terms “neurosurgical techniques,” “brain neoplasm,” “tubular retractor,” “craniotomy,” “stereotactic radiosurgery,” or “ablation” in varying combinations with boolean commands. Only papers that provided relevant data on extent of resection (EOR) and perioperative or postoperative neurological complications were included. Articles were not screened for identification of brain tumor or patient demographics.
Results: Ten articles that complied with the inclusion criteria were incorporated in the literary review. Craniotomy resulted in an EOR average of >77% across all studies, with a complication average of84% and a75% and
Conclusion: Brain neoplasms portray a significant challenge for neurosurgeons because of the brain’s variety of tumor etiologies, location, and extreme sensitivity; these reasons prohibit a singular method to be established. Tumor ablation, when compared to craniotomy and microsurgery with tubular retractors, demonstrated the highest rate of EOR with the least resulting neurological deficits or surgical complications. Craniotomy and microsurgery had comparable EOR, but craniotomy had a higher percentage of morbidities. It is important to note that multiple strategies for craniotomy are performed and there are several modalities of tumor ablation technology, creating a challenge in accurately comparing each approach. It is also worth mentioning that in all cases, the rate of morbidity and mortality correlated to the tumor’s size, location, and etiology (i.e., primary tumor vs. metastasis), and the patient’s age.