Posters
Presentation Type
Poster
Discipline Track
Clinical Science
Abstract Type
Research/Clinical
Abstract
Background: Human papillomavirus (HPV) is the most frequent sexually transmitted infection (STI) and the causal agent of cervical and penile cancers. Globally, 570,000 cases per year in women and 60,000 cases in men are attributable to HPV. HPV types 16 and 18 are the most prevalent high-risk (HR) viral types in tumors. We have used the database of our HPV diagnostic service to determine the prevalence of HR-HPV types in our population (North-Eastern Mexico) and its implications.
Methods: Samples of 50 men and 50 women that were received in our laboratory from 2017 to 2021 were included. These were collected from penile swabs and cervical swabs, respectively. VPH presence was determined by polymerase chain reaction (PCR) and positive cases were subjected to Sanger DNA sequencing for viral genotyping.
Results: In the positive cases of HR-HPV types of women over 40 years of age, the prevalence of viral type 16 was 100%, while in women under 40 years it was only 65%. The same was observed in men with those cases over 40 years of age exhibiting 96% prevalence of this type 16, and only 70% in the under 40 years old cases.
Conclusions: Our findings suggest an inverse association of age with the prevalence of HR-HPV types. This may be due to the introduction of the multivalent vaccines mainly against HPV types 16 and 18 for teenagers in Mexico in 2006.
Recommended Citation
Huitrón-Carrizales, A. L. and Barrera-Saldaña, Hugo A., "Prevalence of high-risk human papillomavirus types in North-Eastern Mexico and implications" (2023). Research Symposium. 79.
https://scholarworks.utrgv.edu/somrs/theme1/posters/79
Included in
Prevalence of high-risk human papillomavirus types in North-Eastern Mexico and implications
Background: Human papillomavirus (HPV) is the most frequent sexually transmitted infection (STI) and the causal agent of cervical and penile cancers. Globally, 570,000 cases per year in women and 60,000 cases in men are attributable to HPV. HPV types 16 and 18 are the most prevalent high-risk (HR) viral types in tumors. We have used the database of our HPV diagnostic service to determine the prevalence of HR-HPV types in our population (North-Eastern Mexico) and its implications.
Methods: Samples of 50 men and 50 women that were received in our laboratory from 2017 to 2021 were included. These were collected from penile swabs and cervical swabs, respectively. VPH presence was determined by polymerase chain reaction (PCR) and positive cases were subjected to Sanger DNA sequencing for viral genotyping.
Results: In the positive cases of HR-HPV types of women over 40 years of age, the prevalence of viral type 16 was 100%, while in women under 40 years it was only 65%. The same was observed in men with those cases over 40 years of age exhibiting 96% prevalence of this type 16, and only 70% in the under 40 years old cases.
Conclusions: Our findings suggest an inverse association of age with the prevalence of HR-HPV types. This may be due to the introduction of the multivalent vaccines mainly against HPV types 16 and 18 for teenagers in Mexico in 2006.