Document Type
Article
Publication Date
3-10-2023
Abstract
Identifying methods to modulate the reactivity of metal hydrides is lacking yet highly desirable given the role they play in a plethora of catalytic applications. Herein we report novel methodology to amplify the reactivity of metal hydrides through the design of well-defined heterometallic bridged hydride species. Catalytic hydroboration of quinolines was dramatically altered by the addition of a secondary metal to bridge the Al–hydride species LAlH. Specifically, the addition of Ni(COD)2 led to the formation of novel heterotrimetallic species 1 which features Ni participating in 3-center bonding with sterically accessible Al–H species and exhibits catalytic hydroboration of sterically encumbered quinolines and approximately a 400 times enhancement in catalytic reactivity in comparison to LAlH.
Recommended Citation
De Leon, Edgardo, et al. "Amplifying Reactivity of Metal Hydrides: A Heterotrimetallic NiAl2 (μ2-H) 2 Catalyst for the Dearomatization of N-Heterocycles." Organometallics 42.6 (2023): 435-440. https://doi.org/10.1021/acs.organomet.2c00668
Publication Title
Organometallics
DOI
https://doi.org/10.1021/acs.organomet.2c00668
Comments
Original published version available at https://doi.org/10.1021/acs.organomet.2c00668