Theses and Dissertations

Date of Award

12-2023

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

First Advisor

Debasish Bandyopadhyay

Second Advisor

Jose Juan Gutierrez-Gonzales

Third Advisor

Pushpa Soti

Abstract

Aloe barbadensis Miller, commonly called Aloe Vera, is a widely popular succulent plant species cultivated across subtropical regions worldwide from India to the Tex-Mex border. Besides its historical uses, Aloe juice has garnered attention as a potential remedy for various ailments, particularly in treating various skin conditions and facilitating wound recovery, including obesity, diabetes, hepatitis, Crohn's disease, and ulcerative colitis. Regrettably, the agricultural practice following sap extraction involves discarding Aloe vera peels, constituting agricultural waste. As part of our continuous research on extraction, isolation, separation, and spectral characterization of value-added chemicals present in waste botanicals herein, we carried out the phytochemical investigation of the dichloromethane (DCM) extract made earlier from the Aloe vera rinds using polarity-based extraction method. A thorough broad-spectrum HPLC-MS analysis facilitated the identification of a diverse range of bioactive compounds, including some molecules that demonstrated pesticidal efficacy. This research involves identifying some biologically active molecules in the DCM extract of the Aloe vera rinds using a combination of column chromatography, flash chromatography, Fourier Transform Infrared spectroscopy (FT-IR), mass spectroscopy (MS), and nuclear magnetic resonance spectroscopy (NMR) techniques.

Comments

Copyright 2023 Nazmul Huda. All Rights Reserved.

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