Theses and Dissertations
Date of Award
5-2016
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Electrical Engineering
First Advisor
Dr. Yoonsu Choi
Second Advisor
Dr. Hasina F. Huq
Third Advisor
Dr. Sanjeev Kumar
Abstract
A scalable microwire peripheral nerve interface was developed, which interacted with regenerated peripheral nerves in microchannel scaffolds. Neural interface technologies are envisioned to facilitate direct connections between the nervous system and external technologies such as limb prosthetics or data acquisition systems for further processing. Presented here is an animal study using a handcrafted microwire regenerative peripheral nerve interface, a novel neural interface device for communicating with peripheral nerves. The neural interface studies using animal models are crucial in the evaluation of efficacy and safety of implantable medical devices before their use in clinical studies.16-electrode microwire microchannel scaffolds were developed for both peripheral nerve regeneration and peripheral nerve interfacing. The microchannels were used for nerve regeneration pathways as a scaffolding material and the embedded microwires were used as a recording electrode to capture neural signals from the regenerated peripheral nerves. Wireless stimulation and recording capabilities were also incorporated to the developed peripheral nerve interface which gave the freedom of the complex experimental setting of wired data acquisition systems and minimized the potential infection of the animals from the wire connections.
Recommended Citation
Ajam, Ali, "Microwire regenerative peripheral nerve interfaces with wireless recording and stimulation capabilities" (2016). Theses and Dissertations. 6.
https://scholarworks.utrgv.edu/etd/6
Comments
Copyright 2016 Ali Ajam. All Rights Reserved.
https://www.proquest.com/dissertations-theses/microwire-regenerative-peripheral-nerve/docview/1810996051/se-2?accountid=7119