The Effects of Salvia hispanica on Biochemical Markers Related to Immune System, Hormone Regulation, and Lumbar Vertebrae in Postmenopausal Rat Model

Author

Daisy M. Mendez, The University of Texas Rio Grande Valley

Date of Award

5-2020

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Biology

First Advisor

Dr. Jameela Banu

Second Advisor

Dr. Joanne Rampersad-Ammons

Third Advisor

Dr. Robert Gilkerson

Abstract

In women, with age and menopause there is increase in body weight and decreased immunity and bone mass. Due to severe side effects of currently available drugs for obesity and bone loss, new therapies with less side effects are sought after and alternative medications are becoming more popular. Recently, Salvia hispanica (SH), a herbal supplement is implicated in losing body weight. Currently, there is no information on how SH modulates obesity or bone health. In this study, effects of SH seed extract was investigated in a postmenopausal rat model on certain hormones, immune markers, and fourth lumbar vertebrae. The highest dose of SH in ovariectomized rats decreased body weight indicating SH reduces body weight gain after menopause. SH modulated hormone and interleukin levels. In the vertebrae, the low and highest dose of SH showed bone protective properties indicating SH has beneficial effects to improve health in postmenopausal women.

Comments

Copyright 2020 Daisy M. Mendez. All Rights Reserved.

https://go.openathens.net/redirector/utrgv.edu?url=https://www.proquest.com/dissertations-theses/effects-em-salvia-hispanica-on-biochemical/docview/2432850835/se-2?accountid=7119

Recommended Citation

Mendez, Daisy M., "The Effects of Salvia hispanica on Biochemical Markers Related to Immune System, Hormone Regulation, and Lumbar Vertebrae in Postmenopausal Rat Model" (2020). Theses and Dissertations. 721.
https://scholarworks.utrgv.edu/etd/721