Theses and Dissertations

Date of Award


Document Type


Degree Name

Master of Science (MS)



First Advisor

Dr. Jameela Banu

Second Advisor

Dr. Joanne Rampersad-Ammons

Third Advisor

Dr. Robert Gilkerson


In women, with age and menopause there is increase in body weight and decreased immunity and bone mass. Due to severe side effects of currently available drugs for obesity and bone loss, new therapies with less side effects are sought after and alternative medications are becoming more popular. Recently, Salvia hispanica (SH), a herbal supplement is implicated in losing body weight. Currently, there is no information on how SH modulates obesity or bone health. In this study, effects of SH seed extract was investigated in a postmenopausal rat model on certain hormones, immune markers, and fourth lumbar vertebrae. The highest dose of SH in ovariectomized rats decreased body weight indicating SH reduces body weight gain after menopause. SH modulated hormone and interleukin levels. In the vertebrae, the low and highest dose of SH showed bone protective properties indicating SH has beneficial effects to improve health in postmenopausal women.


Copyright 2020 Daisy M. Mendez. All Rights Reserved.