Theses and Dissertations
Date of Award
12-2021
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Dr. Shizue Mito
Second Advisor
Dr. Nirakar Sahoo
Third Advisor
Dr. Jose J. Gutierrez
Abstract
The purpose of the research was to synthesize the E stereoisomer of Bilirubin Oxidation Products that had not been synthesized through a total organic synthesis at the start of this project. There were numerous different procedures for the bromination of citraconic anhydride performed in an attempt to optimize yield and purity. A proposed scheme for the total synthesis of the E isomers was constantly updated and altered while the project was ongoing. The bioactivity of the compounds was to be tested if the project had been finished. This might have contributed to a greater understanding of their function and association with subarachnoid hemorrhage induced vasospasm.
Recommended Citation
Ruiz, Tess C., "Total Synthesis of E Stereoisomers of Bilirubin Oxidation Products" (2021). Theses and Dissertations. 957.
https://scholarworks.utrgv.edu/etd/957
Comments
Copyright 2021 Tess Ruiz. All Rights Reserved.
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