Theses and Dissertations

Date of Award

5-1-2026

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Computer Science

First Advisor

Pengfei Gu

Second Advisor

Bin Fu

Third Advisor

Haoteng Tang

Abstract

Medical image segmentation is a fundamental task in computer-aided diagnosis because it enables precise delineation of anatomical structures and pathological regions from clinical images. While convolutional neural networks and Transformer-based models have achieved strong performance on many medical segmentation benchmarks, CNNs struggle to model long-range dependencies and Transformers often incur high computational complexity for high-resolution medical images. Recently, state space models have emerged as an efficient alternative for dense prediction tasks due to their ability to capture long-range dependencies with linear complexity. However, existing Mamba-based segmentation models still rely on pixel-wise raster scanning that disrupts spatial locality and use simple summation to fuse directional features.

This thesis proposes Patch-MoE Mamba, a patch-ordered mixture-of-experts state space architecture that preserves spatial locality through hierarchical patch-based scanning and adaptively fuses directional representations using an MoE-based fusion module. Experiments across seven medical segmentation benchmarks demonstrate strong and consistent performance.

Comments

Copyright 2026 Diego Adame. All Rights Reserved. https://proquest.com/docview/3371493408

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