Human Genetics Publications and Presentations
Submissions from 2024
Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos, Rui Xia, Xueqiu Jian, Amanda L. Rodrigue, Jan Bressler, Eric Boerwinkle, Biqi Cui, Martha L. Daviglus, Charles DeCarli, Linda C. Gallo, and John Blangero
Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos, Ru Xia, Xueqiu Jian, Amanda L. Rodrigue, Jan Bressler, Eric Boerwinkle, Biqi Cui, Martha L. Daviglus, Charles S. DeCarli, Linda C. Gallo, and John Blangero
Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations, Christopher Zdyrski, Vojtech Gabriel, Thea B. Gessler, Abigail Ralston, Itzel Sifuentes-Romero, Debosmita Kundu, Sydney Honold, Hannah Wickham, Marco Arriaga, and Jacob Galan
Short-term HIIT impacts HDL function differently in lean, obese, and diabetic subjects, Lin Zhu, Julia An, Thao Luu, Sara M. Reyna, Puntip Tantiwong, Apiradee Sriwijitkamol, Nicolas Musi, and John M. Stafford
Current and Future Approaches to Pediatric Anxiety Disorder Treatment, André Zugman, Anderson M. Winkler, Purnima Qamar, and Daniel Samuel Pine
Submissions from 2023
Identification of genetic regions associated with Alzheimer ‘s disease blood-based biomarkers in Mexican American families, Marcio A. Almeida
Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts, Habtamu B. Beyene, Corey Giles, Kevin Huynh, Tingting Wang, Michelle Cinel, Natalie A. Mellett, Gavriel Olshansky, Thomas G. Meikle, Gerald F. Watts, and John Blangero
Origin and Evolution of Marsupial-specific Imprinting Clusters Through Lineage-specific Gene Duplications and Acquisition of Promoter Differential Methylation, Wenqi Cao, Kory C. Douglas, Paul B. Samollow, John VandeBerg, Xu Wang, and Andrew G. Clark
Blood transcriptome responses to PFOA and GenX treatment in the marsupial biomedical model Monodelphis domestica, Wenqi Cao, Katharine Horzmann, Bettina Schemera, Myra Petrofski, Trisha Kendall, Jennifer Spooner, Patricia E. Rynders, John Vandeberg, and Xu Wang
Triterpenoid CDDO-EA inhibits lipopolysaccharide-induced inflammatory responses in skeletal muscle cells through suppression of NF-κB, Phoebe Fang-Mei Chang, Daniel Acevedo, Lawrence J. Mandarino, and Sara M. Reyna
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing, Fang Cheng, Xingyan Wang, Seon-Kyeong Jang, Bryan C. Quach, J. Dylan Weissenkampen, Chachrit Khunsriraksakul, Lina Yang, John Blangero, Joanne E. Curran, Ravindranath Duggirala, and Juan M. Peralta
Multimodal study of the neural sources of error monitoring in adolescents and adults, Stefania Conte, John E. Richards, Nathan A. Fox, Emilio A. Valadez, Marco McSweeney, Enda Tan, Daniel Samuel Pine, Anderson M. Winkler, Lucrezia Liuzzi, Elise M. Cardinale, Lauren K. White, and George A. Buzzell
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits, Maria C. Costanzo, Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer, Clint Gilbert, Ryan P. Welch, and John Blangero
Association Of Brain Arterial Diameters With Demographic And Anatomical Factors In A Multinational Pooled Analysis Of Cohort Studies, Victor J. Del Brutto, Farid Khasiyev, Minghua Liu, Antonio Spagnolo-Allende, Ye Qiao, Jesus Melgarejo, Vanessa A. Guzman, Danurys Sanchez, Howard Andrews, and Gladys Maestre
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification, Paul S. de Vries, Matthew P. Conomos, Kuldeep Singh, Christopher J. Nicholson, Deepti Jain, Natalie R. Hasbani, Wanlin Jiang, Sujin Lee, Christian L. Lino Cardenas, Sharon M. Lutz, and John Blangero
Genotype-by-socioeconomic status interaction influences heart disease risk scores and carotid artery thickness in Mexican Americans: the predominant role of education in comparison to household income and socioeconomic index, Vincent P. Diego, Eron G. Manusov, Xi Mao, Joanne E. Curran, Harald H. H. Goring, Marcio Almeida, Michael Mahaney, Juan M. Peralta, John Blangero, and Sarah Williams-Blangero
Relationship Between Cognitive Performance, Physical Activity, and Socio-Demographic/Individual Characteristics Among Aging Americans, Imtiaz Masfique Dowllah, Juan Carlos Lopez-Alvarenga, Gladys Maestre, Ulku S. Karabulut, Michael Lehker, and Murat Karabulut
A longitudinal resource for population neuroscience of school-age children and adolescents in China, Xue-Ru Fan, Yin-Shan Wang, Da Chang, Ning Yang, Meng-Jie Rong, Zhe Zhang, Ye He, Xiaohui Hou, Quan Zhou, and John Blangero
Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study, Bernard Fongang, Claudia Satizabal, Tiffany F. Kautz, Yannick N. Wadop, Jazmyn A. S. Muhammad, Erin Vasquez, Julia Mathews, Monica Gireud-Goss, Michael Mahaney, and Gladys Maestre
Demographic and Clinical Characteristics Associated With Serum GFAP Levels in an Ethnically Diverse Cohort, Mitzi M. Gonzales, Gabriel A. Vela, Vinu Philip, Hector Trevino, Ashley LaRoche, Chen-Pin Wang, Danielle M. Parent, Tiffany F. Kautz, Claudia L. Satizabal, and Gladys Maestre
Co-alteration Network Architecture of Major Depressive Disorder: A Multi-modal Neuroimaging Assessment of Large-scale Disease Effects, Jodie P. Gray, Jordi Manuello, Aaron F. Alexander-Bloch, Cassandra Leonardo, Crystal Franklin, Sueng Choi, Franco Cauda, Tommaso Costa, John Blangero, David C. Glahn, Peter T. Fox, and Helen S. Mayberg
Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Alyssa R. Amod, Max A. Laansma, Laura S. Van Velzen, Moji Aghajani, Kevin Hilbert, Hyuntaek Oh, Ramiro Salas, and Anderson M. Winkler
Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis, Natalie. R. Hasbani, Kenneth E. Westerman, Soo Heon Kwak, Han Chen, Xihao Li, Daniel Di Corpio, Michael C. Mahaney, Ravi Duggirala, Joanne E. Curran, and John Blangero
A sound mind in a sound body: a novel concept unravelling heterogeneity of depression, Gabor Hullam, Zsofia Gal, Xenia Gonda, Tamas Nagy, Andras Gezsi, Isaac Cano, Sandra Van Der Auwera, Mikko Kuokkanen, Peter Antal, and Gabriella Juhasz
Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population, Elizabeth M. Humphries, Kwangmi Ahn, Rachel L. Kember, Fabiana L. Lopes, Evelina Mocci, Juan M. Peralta, John Blangero, David C. Glahn, Fernando S. Goes, and Peter P. Zandi
SINGLE-NUCLEOTIDE POLYMORPHISMS IN THE ABO BLOOD GROUP LOCUS ARE PLEIOTROPICALLY ASSOCIATED WITH THE PLASMA LEVELS OF FACTOR VIII COAGULANT ACTIVITY AND VON WILLEBRAND FACTOR ANTIGEN IN MEXICAN AMERICANS OF SOUTH TEXAS, Shuchita V. Jhaveri, Vincent P. Diego, Marcio Almeida, Hoang Anh T. Nguyen, Juan M. Peralta, Joanne E. Curran, Donna M. Lehman, Ralph A. DeFronzo, Miguel A. Escobar, Raja Rajalingam, Jerry S. Powell, Sarah Williams-Blangero, Ravi Duggirala, John Blangero, and Tom Howard
QuNex—An integrative platform for reproducible neuroimaging analytics, Jie Lisa Ji, Jure Demšar, Clara Fonteneau, Zailyn Tamayo, Lining Pan, Aleksij Kraljic, Andraž Matkovic, Nina Purg, Markus Helmer, and Anderson M. Winkler
Chronic Pulse Wave Velocity And Hemodynamic Responses To Various Training Modes, Murat Karabulut, Jorge Bejar, Alexis Lopez, Michael G. Bemben, Gladys Maestre, and Ulku S. Karabulut
Potential miRNA biomarkers and therapeutic targets for early atherosclerotic lesions, Genesio M. Karere, Jeremy P. Glenn, Ge Li, Ayati Konar, John L. VandeBerg, and Laura A. Cox
A pilot investigation of differential hydroxymethylation levels in patient-derived neural stem cells implicates altered cortical development in bipolar disorder, Ashish Kumar, Mark Z. Kos, Donna Roybal, and Melanie A. Carless
Postmortem Brain Imaging in Alzheimer's Disease and Related Dementias: The South Texas Alzheimer's Disease Research Center Repository, Karl Li, Tanweer Rashid, Jinqi Li, Nicolas Honnorat, Anoop Benet Nirmala, Elyas Fadaee, Di Wang, Sokratis Charisis, Gladys E. Maestre, and Peter T. Fox
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies, Xihao Li, Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Harald H. H. Goring, Michael Mahaney, and Juan M. Peralta
The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs, Gladys E. Maestre, Maria Carrillo, Raj N. Kalaria, Daisy Acosta, Larry Adams, Thierry Adoukonou, Upal Roy, Noe Garza, Jennifer Cahn, and Deepa Roy
Gene-by-Environment Interaction in Non-Alcoholic Fatty Liver Disease and Depression: The Role of Hepatic Transaminases, Eron G. Manusov, Vincent P. Diego, Edward Abrego, Kathryn Herklotz, Marcio A. Almeida, Xi Mao, Sandra L. Laston, John Blangero, and Sarah Williams-Blangero
Frailty index in the Colonias of the Rio Grande Valley: health related quality of life and resilience, Eron G. Manusov, Vincent P. Diego, and Sarah Williams-Blangero
Cocktail-party listening and cognitive abilities show strong pleiotropy, Samuel R. Mathias, Emma M. Knowles, Josephine Mollon, Peter T. Fox, Rene L. Olvera, Juan M. Peralta, Satish Kumar, Harald H. H. Goring, Ravi Duggirala, Joanne E. Curran, John Blangero, and David C. Glahn
Tuberculosis presentation and outcomes in older Hispanic adults from Tamaulipas, Mexico, Belinda Medrano, Miryoung Lee, Gretchen L. Gemeinhardt, Javier E. Rodríguez-Herrera, Moncerrato García-Viveros, and Blanca I. Restrepo
PS-C12-4: OPEN-ANGLE GLAUCOMATOUS OPTIC DAMAGE ASSOCIATED WITH DAYTIME AND NOCTURNAL DIPS IN BLOOD PRESSURE, Jesus Melgarejo, Jan V. Eijgen, Dongmei Wei, Gladys Maestre, Lama A Al Aswad, Luis J. Mena, Thomas Vanassche, Stefan Janssens, Peter Verhamme, and Karel V. Keer
PS-C12-3: OPEN-ANGLE GLAUCOMATOUS OPTIC DAMAGE IN RELATION TO SYSTEMIC AND OCULAR PERFUSION PRESSURE, Jesus Melgarejo, Jan V. Eijgen, Dongmei Wei, Gladys Maestre, Lama A Al Aswad, Luis J. Mena, Thomas Vanassche, Stefan Janssens, Peter Verhamme, and Zhenyu Zhang
Diminishing benefits of urban living for children and adolescents’ growth and development, NCD Risk Factor Collaboration (NCD-RisC), Anu Mishra, Bin Zhou, Andrea Rodriguez-Martinez, Shina Avi, Moran Blychfeld Magnazu, Ronit Endevelt, Jochanan Stessman, Gladys E. Maestre, and Jesus D. Melgarejo
F5_6755A>G, A Nonsynonymous Single-Nucleotide Variation That Substitutes Glycine For Aspartate At Residue 2,194 In The Plasma Blood Clotting Protein Factor V, Is Pleiotropically Associated With Reduced Factor V Coagulant Activity and A Decreased Frailty Index, Hoang Anh Thi Nguyen, Vincent P. Diego, Marcio Almeida, Shuchita Jhaveri, Juan M. Peralta, Joanne E. Curran, Donna M. Lehman, Ralph A. DeFronzo, Raja Rajalingam, Jerry S. Powell, Sarah Williams-Blangero, Ravi Duggirala, John Blangero, and Tom Howard
Dementia and cognitive impairment in French-speaking Sub-Saharan Africa: a comprehensive review on moving out of the shadows of neglect, Cyrille D. Nkouonlack, Wepnyu Y. Njamnshi, Samuel A. Angwafor, Joseph N. Siewe Fodjo, Michel K. Mengnjo, Leonard Ngarka, Maggy Mbede, Leonard N. Nfor, Carlson Abomate, and Gladys E. Maestre
A genome-wide SNP investigation of chemical intolerance, Raymond F. Palmer, Marcio Almeida, Roger B. Perales, and Rudy Rincon
Intracranial Artery Stenosis In Relation To Blood Pressure Components, Dhrumil Patil, Jose Gutierrez, Luis J. Mena, Reinier Leendertz, Carlos Chávez, Egle R. Silva, Joseph Lee, Joseph D. Terwilliger, Jesus Melgarejo, and Gladys Maestre
Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma, Kathryn Recto, Priyadarshini Kachroo, Tianxiao Huan, David Van Den Berg, Gha Young Lee, Helena Bui, Dong Heon Lee, Jessica Gereige, John Blangero, and Joanne E. Curran
Crotalus scutulatus scutulatus Crude Venom and Its Purified Cysteine-Rich Secretory Protein (Css-CRiSP), Armando Reyes, Joseph D. Hatcher, Emelyn Salazar, Jacob Galan, Anton Iliuk, Elda E. Sanchez, and Montamas Suntravat
Proteomic Profiling of Extracellular Vesicles Isolated from Plasma and Peritoneal Exudate in Mice Induced by Crotalus scutulatus scutulatus Crude Venom and Its Purified Cysteine-Rich Secretory Protein (Css-CRiSP), Armando Reyes, Joseph D. Hatcher, Emelyn Salazar, Jacob Galan, Anton Iliuk, Elda E. Sanchez, and Montamas Suntravat
Safety and Immunogenicity of an In Vivo Muscle Electroporation Delivery System for DNA-hsp65 Tuberculosis Vaccine in Cynomolgus Monkeys, Monique Ribeiro de Lima, Ana C. Leandro, Andreia Lamoglia de Souza, Marcio Mantuano Barradas, Eric Henrique Roma, Ana Teresa Gomes Fernandes, Gabrielle Galdino-Silva, Joyce Katiuccia M. Ramos Carvalho, Renato Sergio Marchevsky, and John L. VandeBerg
Serotonin regulation of behavior via large-scale neuromodulation of serotonin receptor networks, Piergiorgio Salvan, Madalena Fonseca, Anderson M. Winkler, Antoine Beauchamp, Jason P. Lerch, and Heidi Johansen-Berg
Mapping Lesion-Related Epilepsy to a Human Brain Network, Frederic L. Schaper, Janne Nordberg, Alexander L. Cohen, Christopher Lin, Joey Hsu, Andreas Horn, Michael A. Ferguson, Shan H. Siddiqi, William Drew, and Anderson M. Winkler
Monodelphis domestica as a Fetal Intra-Cerebral Inoculation Model for Zika Virus Pathogenesis, John Thomas, Juan Garcia, Matthew Terry, Susan M. Mahaney, Oscar Quintanilla, Dionn Carlo Silva, Marisol Morales, and John Vandeberg PhD
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study, Yuxuan Wang, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A. Holdcraft, Donna K. Arnett, Joshua C. Bis, John Blangero, Joanne E. Curran, and Michael C. Mahaney
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis, Joshua S. Weinstock, Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Ravi Duggirala, Joanne E. Curran, John Blangero, Michael C. Mahaney, Juan M. Peralta, and Harald H. H. Goring
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes, Joshua S. Weinstock, Cecelia A. Laurie, Jai G. Broome, Kent D. Taylor, Xiuqing Guo, Alan R. Shuldiner, Jeffrey R. O'Connell, Ravi Duggirala, Joanne E. Curran, and John Blangero
Structural and functional asymmetry of the neonatal cerebral cortex, Logan Z. J. Williams; Sean P. Fitzgibbon; Jelena Bozek; Anderson M. Winkler; Ralica Dimitrova; Tanya Poppe; Andreas Schuh; Antonios Makropoulos,; John Cupitt; and Jonathan O’Muircheartaigh
Clonal haematopoiesis and risk of chronic liver disease, Waihay J. Wong, Connor Emdin, Alexander G. Bick, Seyedeh M. Zekavat, John Blangero, Joanne E. Curran, Ravi Duggirala, Harald H. H. Goring, Michael Mahaney, and Juan M. Peralta
Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts, Yuankai Zhang, Xue Liu, Kerri L. Wiggins, Nuzulul Kurniansyah, Xiuqing Guo, Amanda L. Rodrigue, Wei Zhao, Lisa R. Yanek, Joanne E. Curran, and John Blangero
Country-level gender inequality is associated with structural differences in the brains of women and men, André Zugman, Luz María Alliende, Vicente Medel, Richard A.I. Bethlehem, Jakob Seidlitz, Grace Ringlein, Celso Arango, Aurina Arnatkevičiūtė, Laila Asmal, and Anderson M. Winkler
A systematic review and meta-analysis of resting-state fMRI in anxiety disorders: Need for data sharing to move the field forward, André Zugman, Laura Jett, Chase Antonacci, Anderson M. Winkler, and Daniel Samuel Pine
Submissions from 2022
Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans, Rany Abend, Diana Burk, Sonia G. Ruiz, Andrea L. Gold, Julia L. Napoli, Jennifer C. Britton, Kalina J. Michalska, Tomer Shechner, Anderson M. Winkler, and Ellen Leibenluft
Threat imminence reveals links among unfolding of anticipatory physiological response, cortical-subcortical intrinsic functional connectivity, and anxiety, Rany Abend, Sonia G. Ruiz, Mira A. Bajaj, Anita Harrewijn, Julia O. Linke, Lauren Y. Atlas, Anderson M. Winkler, and Daniel S. Pine
Non-compartmental toxicokinetic studies of the Nigerian Naja nigricollis venom, Auwal A. Bala, Sani Malami, Yusuf Abubakar Muhammad, Binta Kurfi, Ismaila Raji, Sanusi Muhammad Salisu, Mustapha Mohammed, George Oche Ambrose, Murtala Jibril, and Jacob Galan
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis, Janna Marie Bas-Hoogendam, Rachel Bernstein, Brenda E. Benson, Kristin A. Buss, Kelley E. Gunther, Koraly Pérez-Edgar, Giovanni A. Salum, Andrea P. Jackowski, Rodrigo A. Bressan, and Anderson M. Winkler
ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders, Janna Marie Bas-Hoogendam, Nynke A. Groenewold, Moji Aghajani, Gabrielle F. Freitag, Anita Harrewijn, Kevin Hilbert, Neda Jahanshad, Sophia I. Thomopoulos, Paul M. Thompson, and Anderson M. Winkler
Brain charts for the human lifespan, R. A. I. Bethlehem, J. Seidlitz, S. R. White, J. W. Vogel, K. Anderson, C. Adamson, S. Adler, G. S. Alexopoulos, E. Anagnostou, and John Blangero
Experimental Rickettsia typhi Infection in Monodelphis domestica: Implications for Opossums as an Amplifying Host in the Suburban Cycle of Murine Typhus, Lucas S. Blanton, Bethany R. Quade, Alejandro Ramírez-Hernández, Nicole L. Mendell, Alejandro Villasante-Tezanos, Donald H. Bouyet, John L. VandeBerg, and David H. Walker
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders, Gabriëlla A. M. Blokland, Jakob Grove, Chia Yen Chen, Chris Cotsapas, and Ney Alliey Rodriguez
Genetic diversity fuels gene discovery for tobacco and alcohol use, Gretchen R. B. Saunders, Xingyan Wang, Fang Chen, Seon-Kyeong Jang, Mengzhen Liu, Chen Wang, Shuang Gao, John Blangero, Joanne E. Curran, and Ravindranath Duggirala
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease, Gemma Cadby, Corey Giles, Phillip E. Melton, Kevin Huynh, Natalie A. Mellett, Thy Duong, Anh Nguyen, Michelle Cinel, Alex Smith, and John Blangero
Intranasal dexamethasone: a new clinical trial for the control of inflammation and neuroinflammation in COVID-19 patients, Graciela Cárdenas, María Chávez-Canales, Ana María Espinosa, Antonio Jordán-Ríos, Daniel Anica Malagon, Manlio Fabio Márquez Murillo, Laura Victoria Torres Araujo, Ricardo Leopoldo Barajas Campos, Rosa María Wong, and Juan Carlos Lopez Alvarenga
205-LB: ERK Is Required for LPS-Induced TLR4 Internalization in Macrophages, Phoebe Fang-Mei Chang and Sara M. Reyna
Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium, Gabriel A. de Erausquin, Heather Snyder, Traolach S. Brugha, Sudha Seshadri, Maria Carrillo, Rajesh Sagar, Yueqin Huang, Charles Newton, Carmela Tartaglia, John Blangero, Gladys E. Maestre, and Sarah Williams Blangero
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program, Daniel DiCorpo, Sheila M. Gaynor, Emily M. Russell, Kenneth E. Westerman, Laura M. Raffield, Marcio Almeida, Juan M. Peralta, John Blangero, Joanne E. Curran, and Ravindranath Duggirala
SARS-CoV-2 is associated with changes in brain structure in UK Biobank, Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, Paul McCarthy, Frederik Lange, Jesper L. R. Andersson, Ludovica Griffanti, and Anderson M. Winkler
Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium, Lindsay Fernández-Rhodes, Mariaelisa Graff, Victoria L . Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo, Wanying Zhu, John Blangero, Joanne E. Curran, and Ravindranath Duggirala
The gut microbiome is associated with markers of cerebral small vessel disease, Bernard Fongang, Claudia Satizabal, Tiffany F. Kautz, Jayandra J. Himali, Xavier Ramnik, José E. Cavazos, Michael Mahaney, Gladys Maestre, Charles S. DeCarli, and Sudha Seshadri
Genetic influences on dentognathic morphology in the Jirel population of Nepal, Anna M. Hardin, Ryan P. Knigge, Dana L. Duren, Sarah Williams-Blangero, Janardan Subedi, Michael Mahaney, and Richard J. Sherwood
Rare coding variants in RCN3 are associated with blood pressure, Karen Y. He, Tanika N. Kelly, Heming Wang, Jingjing Liang, Luke Zhu, Brian E. Cade, Themistocles L. Assimes, Lewis C. Becker, Amber L. Beitelshees, and Ravi Duggirala
Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes, George Hindy, Peter Dornbos, Mark D. Chaffin, Dajiang J. Liu, Minxian Wang, Margaret Sunitha Selvaraj, John Blangero, Joanne E. Curran, Ravi Duggirala, and Juan M. Peralta
Rare genetic variants explain missing heritability in smoking, Seon-Kyeong Jang, Luke Evans, Allison Fialkowski, Donna K. Arnett, Allison E. Ashley-Koch, Kathleen C. Barnes, Diane M. Becker, Joshua C. Bis, John Blangero, and Eugene R. Bleecker
The Relationship Between Segmental Pulse Wave Velocity And Hemodynamic Variables In Young Hispanic Individuals., Murat Karabulut, Jorge Bejar, Michael G. Bemben, Gladys Maestre, and Ulku S. Karabulut
Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease, Daniel H. Katz, Usman A. Tahir, Alexander G. Bick, Akhil Pampana, Debby Ngo, Mark D. Benson, Zhi Yu, Jeremy M. Robbins, John Blangero, Joanne E. Curran, Ravi Duggirala, Michael C. Mahaney, and Juan M. Peralta
Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension, Tanika N. Kelly, Xiao Sun, Karen Y. He, Michael R. Brown, Sarah A.Gagliano Taliun, Jacklyn N. Hellwege, Marguerite R. Irvin, Juan M. Peralta, John Blangero, and Joanne E. Curran
Human M1 macrophages express unique innate immune response genes after mycobacterial infection to defend against tuberculosis, Arshad Khan, Kangling Zhang, Vipul K. Singh, Abhishek Mishra, Priyanka Kachroo, Tian Bing, Jong Hak Won, Eder Ledezma-Campos, Genesis P. Aguillón-Durán, and Blanca I. Restrepo
Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration, Parmis Khosravi, André Zugman, Paia Amelio, Anderson M. Winkler, and Daniel S. Pine
Genetic determinants of metabolic biomarkers and their associations with cardiometabolic traits in Hispanic/Latino adolescents, Daeeun Kim, Anne E. Justice, Geetha Chittoor, Estela Blanco, Marcio Almeida, Juan M. Peralta, Donna M. Lehman, Joanne E. Curran, Anthony G. Comuzzie, Ravi Duggirala, and John Blangero
Blood-Based miRNA Biomarkers as Correlates of Brain-Based miRNA Expression, Mark Kos, Sobha Puppala, Dianne Cruz, Jennifer L. Neary, Ashish Kumar, Emma Dalan, Cun Li, Peter Nathanielsz, and Melanie A. Carless
Metabolic syndrome predictors of brain gray matter volume in an age-stratified community sample of 776 Mexican- American adults: Results from the genetics of brain structure image archive, Eithan Kotkowski, Larry R. Price, Ralph A. DeFronzo, Crystal G. Franklin, Maximino Salazar, Amy S. Garrett, Mary Woolsey, John Blangero, Ravi Duggirala, David C. Glahn, and Peter T. Fox
Genetic variants in ALDH1L1 and GLDC influence serine to glycine ratio in Hispanic children, Sergey A. Krupenko, Shelley A. Cole, Ruixue Hou, Karin Haack, Sandra Laston, Nitesh R. Mehta, Anthony G. Comuzzie, Nancy F. Butte, and Venkata Saroja Voruganti
Efficient Generation of Functional Hepatocytes from Human Induced Pluripotent Stem Cells for Disease Modeling and Disease Gene Discovery, Satish Kumar, Joanne E. Curran, Sarah Williams-Blangero, and John Blangero
Monodelphis domestica Induced Pluripotent Stem Cells Reveal Metatherian Pluripotency Architecture, Satish Kumar, Erica De Leon, Jose C. Granados, Deanne J. Whitworth, and Jane F. VandeBerg
Influence of the Human Lipidome on Epicardial Fat Volume in Mexican American Individuals, Ana C. Leandro, Laura F. Michael, Marcio Almeida, Mikko Kuokkanen, Kevin Huynh, Corey Giles, Thy Duong, Vincent P. Diego, Ravindranath Duggirala, Geoffrey D. Clarke, John Blangero, and Joanne E. Curran
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies, Zilin Li, Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha Selvaraj, Theodore Arapoglou, Corbin Quick, John Blangero, Joanne E. Curran, Ravindranath Duggirala, and Harald H. H. Goring
A Nonsynonymous-Single-Nucleotide Polymorphism (ns-SNP) in TFPI, the Gene Encoding Tissue Factor Pathway Inhibitor (TFPI), is Pleiotropically Associated with Increased Plasma TFPI Levels and a Decreased Risk of Type 2 Diabetes (T2D) in Mexican Americans of South Texas, Alberto D. Lopez, Vincent P. Diego, Kanisha Patel, Marcio Almeida, Joanne E. Curran, Miguel A. Escobar, Jerry S. Powell, Donna M. Lehman, Ralph A. DeFronzo, Sarah Williams-Blangero, Ravi Duggirala, Laura Almasy, John Blangero, and Tom Howard
Non-alcoholic Fatty Liver Disease and Depression: Evidence for Genotype × Environment Interaction in Mexican Americans, Eron G. Manusov, Vincent P. Diego, Khalid Sheikh, Sandra Laston, John Blangero, and Sarah Williams-Blangero
Editorial: The biology and management of chronic diseases in Mexican Americans, Eron G. Manusov, Belinda M. Reininger, Alfredo Ulloa-Aguirre, and John Blangero
The Genetic contribution to solving the cocktail-party problem, Samuel R. Mathias, Emma Knowles, Josephine Mollon, Amanda Rodrigue, Mary K. Woolsey, Rene L. Olvera, Juan M. Peralta, Satish Kumar, Harald H. H. Goring, Ravi Duggirala, Joanne E. Curran, John Blangero, and David C. Glahn
Patients with chronic pain exhibit individually unique cortical signatures of pain encoding, Astrid Mayr, Pauline Jahn, Anne Stankewitz, Bettina Deak, Anderson M. Winkler, Viktor Witkovsky, Ozan Eren, Andreas Straube, and Enrico Schulz
The Prevalence of Glaucoma in the Jirel Ethnic Group of Nepal, Sarah Miller, Nicholas B. Blackburn, Matthew Johnson, Sandra Laston, Janardan Subedi, Jac C. Charlesworth, John Blangero, Bradford Towne, Suman S. Thapa, and Sarah Williams-Blangero
Human Macrophages Exhibit GM-CSF Dependent Restriction of Mycobacterium tuberculosis Infection via Regulating Their Self-Survival, Differentiation and Metabolism, Abhishek Mishra, Vipul K. Singh, Chinnaswamy Jagannath, Margaret Sunitha Selvaraj, Selvakumar Subbian, Blanca I. Restrepo, Marie-Claire Gauduin, and Arshad Khan
