Human Genetics Publications and Presentations
Submissions from 2018
A genetic association study of carotid intima-media thickness (CIMT) and plaque in Mexican Americans and European Americans with rheumatoid arthritis, Rector Arya, Agustin Escalante, Vidya S. Farook, Jose F. Restrepo, Daniel F. Battafarano, Marcio Almeida, Mark Kos, Marcel Fourcaudot, Srinivas Mummidi, Satish Kumar, Joanne E. Curran, Christopher Jenkinson, John Blangero, Ravi Duggirala, and Inmaculada Del Rincon
Data on genetic associations of carotid atherosclerosis markers in Mexican American and European American rheumatoid arthritis subjects, Rector Arya, Agustin Escalante, Vidya S. Farook, Jose F. Restrepo, Daniel F. Battafarano, Marcio Almeida, Mark Kos, Marcel Fourcaudot, Srinivas Mummidi, Satish Kumar, Joanne E. Curran, Christopher Jenkinson, John Blangero, Ravi Duggirala, and Inmaculada Del Rincon
Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents, Rector Arya, Vidya S. Farook, Sharon P. Fowler, Sobha Puppala, Geetha Chittoor, Roy G. Resendez, Srinivas Mummidi, Jairam Vanamala, Laura Almasy, Joanne E. Curran, Donna M. Lehman, Christopher P. Jenkinson, Jane L. Lynch, Ralph A. DeFronzo, John Blangero, Ravindranath Duggirala, and Vincent P. Diego
Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling, Minwoo Baek, Mihwa Kim, Jae Sung Lim, Liza D. Morales, Joselin Hernandez, Srinivas Mummidi, Sarah Williams-Blangero, Ik-Soon Jang, Andrew Tsin, and Dae Joon Kim
Genetic Variants Related to Cardiometabolic Traits Are Associated to B Cell Function, Insulin Resistance, and Diabetes Among AmeriCan Indians: The Strong Heart Family Study, Poojitha Balakrishnan, Dhananjay Vaidya, Venkata Saroja Voruganti, Karin Haack, Jack W. Kent Jr., Kari E. North, Sandra Laston, Barbara V. Howard, Jason G. Umans, and Elisa T. Lee
Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships, Nicholas B. Blackburn, Arthur Porto, Juan M. Peralta, and John Blangero
Contribution of Inbred Singletons to Variance Component Estimation of Heritability and Linkage, Lucy Blondell, August N. Blackburn, Mark Kos, John Blangero, and Harald HH Goring
Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics, René Breuer, Manuel Mattheisen, Josef Frank, Bertram Krumm, and Ney Alliey Rodriguez
Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study, Gemma Cadby, Phillip E. Melton, Nina S. McCarthy, Marcio Almeida, Sarah Williams-Blangero, Joanne E. Curran, Jane F. VandeBerg, Jennie Hui, John Beilby, A. W. Musk, Alan L. James, Joseph Hung, John Blangero, and Eric K. Moses
Neurodegenerative disease biomarkers Aβ1–40, Aβ1–42, tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy, Jason A. Chen, Scott C. Fears, Anna J. Jasinska, Alden Huang, Noor B. Al-Sharif, Kevin E. Scheibel, Thomas D. Dyer, Anne M. Fagan, John Blangero, M. J. Jorgensen, J. R. Kaplan, N. B. Freimer, and Giovanni Coppol
The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function, Xi Chen, Iriscilla Ayala, Chris Shannon, Marcel Fourcaudot, Nikhil K. Acharya, Christopher Jenkinson, Sami Heikkinen, and Luke Norton
TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart, Nitin A. Das, Andrea J. Carpenter, Tadashi Yoshida, Senthil A. Kumar, Sandeep Gautam, Ricardo Mostany, Reza Izadpanah, Ashok Kumar, Srinivas Mummidi, Ulrich Siebenlist, and Bysani Chandrasekar
Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients, C Gustavo De Moraes, Michele Petitto, Juan B. Yepez, Anavaj Sakuntabhai, Etienne Simon-Loriere, Mussaret B. Zaidi, Matthieu Prot, Claude Ruffie, Susan S. Kim, and Gladys E. Maestre
Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model, Jubao Duan, Harald H. H. Goring, Alan R. Sanders, Winton Moy, Jessica Freda, Eugene I. Drigalenko, Mark Kos, Deli He, and Pablo V. Gejman
Fast and Powerful Genome Wide Association of Dense Genetic Data with High Dimensional Imaging Phenotypes, Habib Ganjgahi, Anderson M. Winkler, David C. Glahn, John Blangero, Brian Donohue, Peter Kochunov, and Thomas E. Nichols
Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS), Chuan Gao, Keri L. Tabb, Latchezar Dimitrov, Kent D. Taylor, Nan Wang, Xiuqing Guo, Jirong Long, Jerome I. Rotter, Richard M. Watanabe, Joanne E. Curran, and John Blangero
Genetic analysis of deep phenotyping projects in common disorders, Elliot S. Gershon, Godfrey Pearlson, Matcheri S. Keshavan, Carol Tamminga, and Ney Alliey Rodriguez
Additive genetic variation in the craniofacial skeleton of baboons (genus Papio) and its relationship to body and cranial size, Jessica L. Joganic, Katherine E. Willmore, Joan T. Richtsmeier, Kenneth M. Weiss, Michael Mahaney, Jeffrey Rogers, and James M. Cheverud
Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees, Goo Jun, Alisa K. Manning, Marcio Almeida, Matthew Zawistowski, Andrew R. Wood, Thomas D. Dyer, Juan M. Peralta, Joanne E. Curran, Ravi Duggirala, and John Blangero
Whole genome sequencing of 91 multiplex schizophrenia families reveals increased burden of rare, exonic copy number variation in schizophrenia probands and genetic heterogeneity, Fayeza F. Khan, Phillip E. Melton, Nina S. McCarthy, Bharti Morar, John Blangero, Eric K. Moses, and Assen Jablensky
Disentangling the genetic overlap between cholesterol and suicide risk, Emma Knowles, Joanne E. Curran, Peter J. Meikle, Kevin Huynh, Samuel R. Mathias, Harald H. H. Goring, John L. VandeBerg, Michael Mahaney, Rene L. Olvera, Ravi Duggirala, Laura Almasy, David C. Glahn, and John Blangero
Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery, Mark Z. Kos, Jubao Duan, Alan R. Sanders, Lucy Blondell, Eugene I. Drigalenko, Melanie A. Carless, Pablo V. Gejman, and Harald H. H. Goring
Diet-induced early-stage atherosclerosis in baboons: lipoproteins, atherogenesis, and arterial compliance, Michael Mahaney, Genesio M. Karere, David L. Rainwater, Venkata Saroja Voruganti, Edward J. Dick Jr, Michael Owston, Karen S. Rice, Laura Cox, Anthony G. Comuzzie, and John L. VandeBerg
Improving genetic prediction by leveraging genetic correlations among human diseases and traits, Robert M. Maier, Zhihong Zhu, Sang Hong Lee, Maciej Trzaskowski, and Ney Alliey Rodriguez
Deficits in visual working-memory capacity and general cognition in African Americans with psychosis, Samuel R. Mathias, Emma E. Knowles, Jennifer Barrett, Tamara Beetham, Olivia Leach, Sebastiano Buccheri, Katrina Aberizk, John Blangero, Russell A. Poldrack, and David C. Glahn
Assessment of Cognition and Personality as Potential Endophenotypes in the Western Australian Family Study of Schizophrenia, Nina S. McCarthy, Johanna C. Badcock, Melanie L. Clark, Emma E. M. Knowles, Gemma Cadby, Phillip E. Melton, Vera A. Morgan, John Blangero, Eric K. Moses, David C. Glahn, and Assen Jablensky
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals, Pradeep Natarajan, Gina M. Peloso, Seyedeh M. Zekavat, May Montasser, Andrea Ganna, Mark Chaffin, Amit V. Khera, John Blangero, Joanne E. Curran, and Michael C. Mahaney
Epigenetics, heritability and longitudinal analysis, Haakon E. Nustad, Marcio Almeida, Angelo J. Canty, Marissa LeBlanc, Christian M. Page, and Phillip E. Melton
Genome-wide linkage scan for loci influencing plasma triglyceride levels, Juan M. Peralta, Nicholas B. Blackburn, Arthur Porto, John Blangero, and Jac C. Charlesworth
Reliability of genomic predictions of complex human phenotypes, Arthur Porto, Juan M. Peralta, Nicholas B. Blackburn, and John Blangero
Concordance between point-of-care blood gas analysis and laboratory autoanalyzer in measurement of hemoglobin and electrolytes in critically ill patients, Shivesh Prakash, Shailesh Bihari, Zhan Y. Lim, Santosh Verghese, Hemant Kulkarni, and Andrew D. Bersten
Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection, Monica D. Ramstetter, Suchila A. Shenoy, Thomas D. Dyer, Donna M. Lehman, Joanne E. Curran, Ravindranath Duggirala, John Blangero, Jason G. Mezey, and Amy L. Williams
Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groups, Blanca I. Restrepo, Léanie Kleynhans, Alejandra B. Salinas, Bassent Abdelbary, Happy Tshivhula, Genesis P. Aguillón-Durán, Carine Kunsevi-Kilola, Gloria Salinas, Kim Stanley, and Juan C. Lopez-Alvarenga
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population, Manuel A. Rivas, Brandon E. Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M. Neale, Mitja Kurki, John Blangero, and Joanne E. Curran
Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach, Maria Elena Romero-Ibarguengoitia, Felipe Vadillo-Ortega, Augusto Enrique Caballero, Isabel Ibarra-Gonzalez, Arturo Herrera-Rosas, Maria Fabiola Serratos-Canales, Mireya Leon-Hernandez, Antonio Gonzalez-Chavez, Srinivas Mummidi, Ravindranath Duggirala, and Juan Carlos Lopez Alvarenga
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes, Douglas M. Ruderfer, Stephan Ripke, Andrew McQuillin, James Boocock, and Ney Alliey Rodriguez
Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus), C. A. Schmitt, S. K. Service, A. J. Jasinska, Thomas D. Dyer, M. J. Jorgensen, R. M. Cantor, G. M. Weinstock, John Blangero, J. R. Kaplan, and N. B. Freimer
Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls, Rebecca Shafee, Pranav Nanda, Jaya L. Padmanabhan, Neeraj Tandon, and Ney Alliey Rodriguez
Association of common polymorphisms in the VEGFA and SIRT1 genes with type 2 diabetes-related traits in Mexicans, Armando Totomoch-Serra, Maria de Lourdes Muñoz, Juan Burgueño, Maria Cristina Revilla-Monsalve, and Alvaro Diaz-Badillo
Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity, Dennis van der Meer, Pieter J. Hoekstra, Daan van Rooij, Anderson M. Winkler, Hanneke van Ewijk, Dirk J. Heslenfeld, Jaap Oosterlaan, Stephen V. Faraone, Barbara Franke, and Jan K. Buitelaar
Joint Analysis of Cortical Area and Thickness as a Replacement for the Analysis of the Volume of the Cerebral Cortex, Anderson M. Winkler, Douglas N. Greve, Knut J. Bjuland, Thomas E. Nichols, Mert R. Sabuncu, Asta K. Håberg, Jon Skranes, and Lars M. Rimol
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries, Seyedeh M. Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan Bloom, Timothy Poterba, Laura Almasy, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Juan M. Peralta, and Harald H. H. Goring
Submissions from 2017
Reproducibility of tract-based white matter microstructural measures using the ENIGMA-DTI protocol, Ashley Acheson, S Andrea Wijtenburg, Laura M. Rowland, Anderson M. Winkler, Charles W. Mathias, L Elliot Hong, Neda Jahanshad, Binish Patel, Nancy L. Thompson, and Stephen A. McGuire
Association of Cardiometabolic Genes with Arsenic Metabolism Biomarkers in American Indian Communities: The Strong Heart Family Study (SHFS), Poojitha Balakrishnan, Dhananjay Vaidya, Nora Franceschini, V. Saroja Voruganti, Matthew O. Gribble, Karin Haack, Sandra Laston, Jason G. Umans, Kevin A. Francesconi, and Walter Goessler
Improvement of cardiometabolic markers after fish oil intervention in young Mexican adults and the role of PPARα L162V and PPARγ2 P12A, Aristea Binia, Carolina Vargas-Martínez, Mónica Ancira-Moreno, Laura M. Gosoniu, Ivan Montoliu, Elí Gámez-Valdez, Diana C. Soria-Contreras, Adriana Angeles-Quezada, Rocío Gonzalez-Alberto, and Juan Carlos Lopez Alvarenga
Evaluating a CLL susceptibility variant in ITGB2 in families with multiple subtypes of hematological malignancies, Nicholas B. Blackburn, James R. Marthick, Annette Banks, Jac C. Charlesworth, Katherine A. Marsden, Ray M. Lowenthal, John Blangero, and Joanne L. Dickinson
Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study, Geetha Chittoor, Karin Haack, Nitesh R. Mehta, Sandra Laston, Shelley A. Cole, Anthony G. Comuzzie, Nancy F. Butte, and V. Saroja Voruganti
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation, Audrey Y. Chu, Xuan Deng, Virginia A. Fisher, Alexander Drong, Yang Zhang, Mary F. Feitosa, Ching-Ti Liu, Olivia Weeks, Audrey C. Choh, Qing Duan, and Thomas D. Dyer
The heritability of multi-modal connectivity in human brain activity, Giles L. Colclough, Stephen M. Smith, Thomas E. Nichols, Anderson M. Winkler, Stamatios N. Sotiropoulos, Matthew F. Glasser, David C. Van Essen, and Mark W. Woolrich
Nonhuman Primates and Translational Research—Cardiovascular Disease, Laura Cox, Michael Olivier, Kimberly D. Spradling-Reeves, Genesio M. Karere, Anthony G. Comuzzie, and John L. VandeBerg
Investigating resting-state functional connectivity in the cervical spinal cord at 3T, Falk Eippert, Yazhuo Kong, Anderson M. Winkler, Jesper L. Andersson, Jürgen Finsterbusch, Christian Büchel, Jonathan C. Brooks, and Irene Tracey
Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children, Vidya S. Farook, Lavanya Reddivari, Srinivas Mummidi, Sobha Puppala, Rector Arya, Juan Carlos Lopez Alvarenga, Sharon P. Fowler, Roy G. Resendez, Joanne E. Curran, Christopher Jenkinson, John Blangero, and Ravi Duggirala
Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours, Liesel M. FitzGerald, Kelsie Raspin, James R. Marthick, Matt A. Field, Roslyn C. Malley, Russell J. Thomson, Nicholas B. Blackburn, Erika Banks, Annette Banks, Jac C. Charlesworth, Shaun Donovan, and Joanne L. Dickinson
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls, Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M. Teslovich, Vineeta Agarwala, Kyle J. Gaulton, Lizz Caulkins, Rector Arya, Ravi Duggirala, Joanne E. Curran, Satish Kumar, and John Blangero
Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease, Andrew S. Flies, Nicholas B. Blackburn, Alan Bruce Lyons, John D. Hayball, and Gregory M. Woods
Effects of Conjugated Linoleic Acid and Metformin on Insulin Sensitivity in Obese Children: Randomized Clinical Trial, Nayely Garibay-Nieto, Gloria Queipo-García, Flor Alvarez, Mayra Bustos, Erendira Villanueva, Fernando Ramírez, Mireya León, Estibalitz Laresgoiti-Servitje, Juan Carlos Lopez Alvarenga, and Ravi Duggirala
Optimal echo time for functional MRI of the infant brain identified in response to noxious stimulation, Sezgi Goksan, Caroline Hartley, Samuel A. Hurley, Anderson M. Winkler, Eugene P. Duff, Mark Jenkinson, Richard Rogers, Stuart Clare, and Rebeccah Slater
How many more? Sample size determination in studies of morphological integration and evolvability, Mark Grabowski and Arthur Porto
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults, Mariaelisa Graff, Robert A. Scott, Anne E. Justice, Kristin L. Young, Mary F. Feitosa, Llilda Barata, Thomas W. Winkler, Audrey Y. Chu, Anubha Mahajan, and John Blangero
Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits, Felix Grassmann, Christina Kiel, Martina E. Zimmermann, Mathias Gorski, Veronika Grassmann, Klaus Stark, Iris M. Heid, Bernhard H.F. Weber, Lars G. Fritsche, and John Blangero
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex, Tulio Guadalupe, Samuel R. Mathias, Theo G. M. vanErp, Christopher D. Whelan, Marcel P. Zwiers, Yoshinari Abe, Lucija Abramovic, Ingrid Agartz, Ole A. Andreassen, and John Blangero
Hyperinsulinemia and elevated systolic blood pressure independently predict white matter hyperintensities with associated cognitive decrement in the middle-aged offspring of dementia patients, Keith A. Hawkins, Nazli Emadi, Godfrey D. Pearlson, Anderson M. Winkler, Beth Taylor, Latha Dulipsingh, Diana King, Brian Pittman, and Karen Blank
Novel genetic loci associated with hippocampal volume, Derrek P. Hibar, Hieab H. H. Adams, Neda Jahanshad, Ganesh Chauhan, Jason L. Stein, Edith Hofer, Miguel E. Renteria, Joshua C. Bis, Laura Almasy, John Blangero, Joanne E. Curran, Ravi Duggirala, and Harald H. H. Goring
The genetic basis of the comorbidity between cannabis use and major depression, Karen Hodgson, Laura Almasy, Emma E. M. Knowles, Jack W. Kent Jr., Joanne E. Curran, Thomas D. Dyer, Harald H. H. Goring, Rene L. Olvera, Mary D. Woolsey, Ravindranath Duggirala, Peter T. Fox, John Blangero, and David C. Glahn
Epigenetic Age Acceleration Assessed with Human White-Matter Images, Karen Hodgson, Melanie A. Carless, Hemant Kulkarni, Joanne E. Curran, Emma Sprooten, Emma E. Knowles, Samuel R. Mathias, Harald H. H. Goring, Nailin Yao, Rene L. Olvera, Laura Almasy, Ravindranath Duggirala, John Blangero, and David C. Glahn
Lack of Trypanosoma cruzi Infection in Urban Roof Rats (Rattus rattus) at a Texas Facility Housing Naturally Infected Nonhuman Primates, Carolyn L. Hodo, Nicole R. Bertolini, John C. Bernal, John L. VandeBerg, and Sarah A. Hamer
Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation, Wen-Chi Hsueh, Anup K. Nair, Sayuko Kobes, Peng Chen, Harald H. H. Goring, Toni I. Pollin, Alka Malhotra, William C. Knowler, Leslie J. Baier, and Robert L. Hanson
Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity, Terumasa Ikeda, Mayuko Shimoda, Diako Ebrahimi, John L. VandeBerg, Reuben S. Harris, Atsushi Koito, and Kazuhiko Maeda
Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primate, Anna J. Jasinska, Ivette Zelaya, Susan K. Service, Christine B. Peterson, Rita M. Cantor, Oi-Wa Choi, Joseph DeYoung, Eleazar Eskin, Lynn A. Fairbanks, John Blangero, and Thomas D. Dyer
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits, Anne E. Justice, Thomas W. Winkler, Mary F. Feitosa, Misa Graff, Virginia A. Fisher, Kristin Leonard, Kristin Young, Llilda Barata, Xuan Deng, John Blangero, and Joanne E. Curran
Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation, Bernadet L. Klaassens, Serge A. Rombouts, Anderson M. Winkler, Helene C. van Gorsel, Jeroen van der Grond, and Joop M A van Gerven
The Lipidome in Major Depressive Disorder: Shared Genetic Influence for Ether-Phosphatidylcholines, a Plasma-Based Phenotype Related to Inflammation, and Disease Risk, Emma E. M. Knowles, Kevin Huynh, Peter J. Meikle, Harald H. H. Goring, Rene L. Olvera, Samuel R. Mathias, Ravi Duggirala, Laura Almasy, John Blangero, Joanne E. Curran, and David C. Glahn
Serum phosphatidylinositol as a biomarker for bipolar disorder liability, Emma E. M. Knowles, Peter J. Meikle, Kevin Huynh, Harald H. H. Goring, Rene L. Olvera, Samuel R. Mathias, Ravi Duggirala, Laura Almasy, John Blangero, Joanne E. Curran, and David C. Glahn
Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance, Mark Kos, Melanie A. Carless, Juan M. Peralta, Joanne E. Curran, Ellen E. Quillen, Marcio Almeida, August N. Blackburn, Lucy Blondell, David Roalf, Michael F. Pogue-Geile, Harald H. H. Goring, and Laura Almasy
Lipidomics in the Study of Hypertension in Metabolic Syndrome, Hemant Kulkarni, Manju Mamtani, John Blangero, and Joanne E. Curran
Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families, Hemant Kulkarni, Manju Mamtani, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael Mahaney, Anthony G. Comuzzie, Ravindranath Duggirala, Peter J. Meikle, John Blangero, and Joanne E. Curran
TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis, Nicole J. Lake, Rachael L. Taylor, Hugh Trahair, K. N. Harikrishnan, Joanne E. Curran, Marcio Almeida, Hemant Kulkarni, Matthew P. Johnson, Thomas D. Dyer, Michael Mahaney, Harald H. H. Goring, and John Blangero
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study, R. Lencer, L. J. Mills, Ney Alliey-Rodriguez, and R. Shafee
Heart Failure–Related Hyperphosphorylation in the Cardiac Troponin IC Terminus Has Divergent Effects on Cardiac Function In Vivo, Yuejin Li, Guangshuo Zhu, Nazareno Paolocci, Pingbo Zhang, Cyrus Takahashi, Nazli Okumus, Amir Heravi, Gizem Keceli, Genaro A. Ramirez-Correa, and David A. Kass
Factores de riesgo asociados a recaída de enfermedad por reflujo gastroesofágico en pacientes de primer nivel de atención exitosamente tratados con inhibidor de la bomba de protones [Risk factors associated with gastroesophageal reflux disease relapse in primary care patients successfully treated with a proton pump inhibitor], Aurelio López-Colombo, M. S. Pacio-Quiterio, L. Y. Jesús-Mejenes, J. E. G. Rodríguez-Aguilar, M. López-Guevara, A. J. Montiel-Jarquín, Juan Carlos Lopez Alvarenga, E. R. Morales-Hernández, V. R. Ortiz-Juárez, and L. Ávila-Jiménez
Rare, Potentially Pathogenic Variants in ZNF469 Are Not Enriched in Keratoconus in a Large Australian Cohort of European Descent, Sionne E. M. Lucas, Tiger Zhou, Nicholas B. Blackburn, Richard A. Mills, Jonathan Ellis, Paul Leo, Emmanuelle Souzeau, Bronwyn Ridge, Jac C. Charlesworth, and Matthew A. Brown
A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk, Alisa Manning, Heather M. Highland, Jessica Gasser, Xueling Sim, Taru Tukiainen, Pierre Fontanillas, Niels Grarup, Manuel A. Rivas, Anubha Mahajan, and John Blangero
The Processing-Speed Impairment in Psychosis Is More Than Just Accelerated Aging, Samuel R. Mathias, Emma E. M. Knowles, Jennifer Barrett, Olivia Leach, Sebastiano Buccheri, Tamara Beetham, John Blangero, Russell A. Poldrack, and David C. Glahn
Exome array analysis suggests an increased variant burden in families with schizophrenia, Nina S. McCarthy, Phillip E. Melton, Sarah V. Ward, Spencer M. Allan, Milan Dragovic, Melanie L. Clark, Bharti Morar, Justin P. Rubio, John Blangero, and Johanna C. Badcock
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes, Josep M. Mercader, Rachel G. Liao, Avery D. Bell, Zachary Dymek, Karol Estrada, Taru Tukiainen, Alicia Huerta-Chagoya, Hortensia Moreno-Macías, Joanne E. Curran, John Blangero, Ravi Duggirala, and Christopher Jenkinson
Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer, Huân M. Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, and Ney Alliey Rodriguez
Detection and Risk Stratification of Women at High Risk of Preterm Birth in Rural Communities near Nagpur, India, Archana Patel, Amber Abhijeet Prakash, Yamini V. Pusdekar, Hemant Kulkarni, and Patricia Hibberd
The effect size of type 2 diabetes mellitus on tuberculosis drug resistance and adverse treatment outcomes, Lucia Monserrat Perez-Navarro, Blanca I. Restrepo, Francisco Javier Fuentes-Dominguez, Ravi Duggirala, Jaime Morales-Romero, Juan Carlos Lopez Alvarenga, Iñaki Comas, and Roberto Zenteno-Cuevas
Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives, Monica D. Ramstetter, Thomas D. Dyer, Donna M. Lehman, Joanne E. Curran, Ravindranath Duggirala, John Blangero, Jason G. Mezey, and Amy L. Williams
Heritability and genetic correlation between GERD symptoms severity, metabolic syndrome, and inflammation markers in families living in Mexico City, Arturo Reding-Bernal, Valentin Sánchez-Pedraza, Hortensia Moreno-Macías, Sergio Sobrino-Cossio, María Elizabeth Tejero-Barrera, Ana Isabel Burguete-García, Mireya Leon-Hernandez, María Fabiola Serratos-Canales, Ravi Duggirala, and Juan Carlos Lopez Alvarenga
Nonalcoholic fatty liver disease can be predicted by retinal vascular changes in patients with obesity without hypertension or diabetes, Maria Elena Romero-Ibarguengoitia, Arturo Herrera-Rosas, Alfredo A. Domínguez-Mota, Jinny T. Camas-Benitez, María F. Serratos-Canales, Mireya León-Hernández, Antonio González-Chávez, Srinivas Mummidi, Ravi Duggirala, and Juan Carlos Lopez Alvarenga
Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis, Alan R. Sanders, Eugene I. Drigalenko, Jubao Duan, Jessica Freda, Harald H. H. Goring, and Pablo V. Gejman
Whole Genome Sequencing in Psychiatric Disorders: the WGSPD Consortium, Stephan J. Sanders, Benjamin M. Neale, Hailiang Huang, Donna M. Werling, Joon-Yong An, Shan Dong, Goncalo Abecasis, P. Alexander Arguello, John Blangero, and Michael Boehnke
Sympathetic nervous system activity and anti-lipolytic response to iv-glucose load in subcutaneous adipose tissue of obese and obese type 2 diabetic subjects, Uwe Schumann, Christopher P. Jenkinson, Andreas Alt, Martina Zügel, Jürgen M. Steinacker, and Marion Flechtner-Mors
Associations between self-reported sleep quality and white matter in community-dwelling older adults: A prospective cohort study, Claire E. Sexton, Enikő Zsoldos, Nicola Filippini, Ludovica Griffanti, Anderson M. Winkler, Abda Mahmood, Charlotte L. Allan, Anya Topiwala, Simon D. Kyle, and Kai Spiegelhalder
Analysis of whole exome sequencing with cardiometabolic traits using family-based linkage and association in the IRAS Family Study, Keri L. Tabb, Jacklyn N. Hellwege, Nicholette D. Palmer, Latchezar Dimitrov, Satria Sajuthi, Kent D. Taylor, Maggie C.Y. NG, Gregory A. Hawkins, Yii-Der Ida Chen, and John Blangero
Ontogeny of myosin isoform expression and prehensile function in the tail of the gray short-tailed opossum ( Monodelphis domestica), Dylan R. Thomas, Brad A. Chadwell, Gary R. Walker, Julio E. Budde, John L. VandeBerg, and Michael T. Butcher
Protective Effect of Anti-Phosphatidylserine Antibody in a Guinea Pig Model of Advanced Hemorrhagic Arenavirus Infection, John M. Thomas and Philip E. Thorpe
Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease, Danielle Marquete Vitelli-Avelar, Renato Sathler-Avelar, Armanda Moreira Mattoso-Barbosa, Nicolas Gouin, Marcelo Perdigão-de-Oliveira, Leydiane Valério-Dos-Reis, Ronaldo Peres Costa, Silvana Maria Elói-Santos, Jane F. VandeBerg, and John Vandeberg
The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia, Liv Cecilie V. Thomsen, Nina S. McCarthy, Phillip E. Melton, Gemma Cadby, and Rigmor Austgulen
