Human Genetics Publications and Presentations

 

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Submissions from 2017

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Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation, Maria Warnefors, Katharina Mössinger, Jean Halbert, Anja Studer, Tania Studer, John L. VandeBerg, Isa Lindgren, Amir Fallahshahroudi, Per Jensen, and Henrik Kaessmann

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ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice, Lakshini Weerasekera, Caroline Rudnicka, Qing-Xiang Sang, Joanne E. Curran, Matthew P. Johnson, Eric K. Moses, Harald H. H. Goring, John Blangero, Jana Hricova, Markus Schlaich, and Vance B. Matthews

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Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia, S. H. Witt, F. Streit, M. Jungkunz, J. Frank, and Ney Alliey Rodriguez

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Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families, M. Woodbury-Smith, D. A. Bilder, J. Morgan, L. Jerominski, T. Darlington, Thomas D. Dyer, A. D. Paterson, and H. Coon

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Transition from pre-diabetes to diabetes and predictors of risk in Mexican-Americans, Shenghui Wu, Joseph B. Mccormick, Joanne E. Curran, and Susan P. Fisher-Hoch

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Molecular Profiling of Human Induced Pluripotent Stem Cell-Derived Hypothalamic Neurones Provides Developmental Insights into Genetic Loci for Body Weight Regulation, L. Yao, Y. Liu, Satish Kumar, Joanne E. Curran, John Blangero, Y. Chen, and Donna M. Lehman

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Inferring pathobiology from structural MRI in schizophrenia and bipolar disorder: Modeling head motion and neuroanatomical specificity, Nailin Yao, Anderson M. Winkler, Jennifer Barrett, Gregory A. Book, Tamara Beetham, Rachel Horseman, Olivia Leach, Karen Hodgson, and Emma M. Knowles

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Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data, Hua Zhou, John Blangero, Thomas D. Dyer, Kei-hang K. Chan, Kenneth Lange, and Eric M. Sobel

Submissions from 2016

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Novel Genetic Loci Underlying Human Intracranial Volume Identified through Genome-Wide Association, Hieab HH Adams, Derrek P. Hibar, Vincent Chouraki, Jason L. Stein, Paul A. Nyquist, Miguel E. Rentería, Stella Trompet, John Blangero, Joanne E. Curran, Ravi Duggirala, and Harald HH Goring

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Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity, Omar Ali, Diana Cerjak, Jack W. Kent Jr, Roland James, John Blangero, Melanie A. Carless, and Yi Zhang

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Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke, Claire Allman, Ugwechi Amadi, Anderson M. Winkler, Leigh Wilkins, Nicola Filippini, Udo Kischka, Charlotte J. Stagg, and Heidi Johansen-Berg

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Independent test assessment using the extreme value distribution theory, Marcio Almeida, Lucy Blondell, Juan M. Peralta, Jack W. Kent Jr., Goo Jun, Tanya M. Teslovich, Christian Fuchsberger, Andrew R. Wood, Alisa K. Manning, Thomas D. Dyer, Ravindranath Duggirala, and John Blangero

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Interactions Between Alcohol Metabolism Genes and Religious Involvement in Association With Maximum Drinks and Alcohol Dependence Symptoms, Karen G. Chartier, Danielle M. Dick, Laura Almasy, Grace Chan, Fazil Aliev, Marc A. Schuckit, Denise M. Scott, John Kramer, Kathleen K. Bucholz, and Laura J. Bierut

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GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans, Geetha Chittoor, Jack W. Kent Jr., Marcio Almeida, Sobha Puppala, Vidya S. Farook, Shelley A. Cole, Karin Haack, Harald H. H. Goring, Jean W. MacCluer, Joanne E. Curran, Melanie A. Carless, Matthew P. Johnson, Eric K. Moses, Laura Almasy, Michael C. Mahaney, Donna M. Lehman, Ravindranath Duggirala, Anthony G. Comuzzie, John Blangero, and Venkata Saroja Voruganti

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The Quantitative-MFG Test: A linear mixed effect model to detect maternal-offspring gene interactions, Michelle M. Clark, John Blangero, Thomas D. Dyer, Eric M. Sobel, and Janet S. Sinsheimer

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Distribution of Six Polymorphisms in Two Communities with a Historical High Incidence of Diabetes and Obesity in Yucatan, Mexico, Miriam Givisay Domínguez-Cruz, María de Lourdes Muñoz, Armando Totomoch-Serra, María Guadalupe García-Escalante, Nina Valadez-González, Doris Pinto-Escalante, and Alvaro Diaz-Badillo

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Genetic Analysis Workshop 19: methods and strategies for analyzing human sequence and gene expression data in extended families and unrelated individuals, Corinne D. Engelman, Celia M T Greenwood, Julia N. Bailey, Rita M. Cantor, Jack W. Kent Jr, Inke R. König, Justo Lorenzo Bermejo, Phillip E. Melton, Stephanie A. Santorico, and Laura Almasy

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Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof-of-concept and roadmap for future studies, Barbara Franke, Jason L. Stein, Stephan Ripke, Verneri Anttila, Derrek P. Hibar, Kimm J. E. van Hulzen, Alejandro Arias-Vasquez, Jordan W. Smoller, Thomas E. Nichols, and Anderson M. Winkler

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Filtering genetic variants and placing informative priors based on putative biological function, Stefanie Friedrichs, Dörthe Malzahn, Elizabeth W. Pugh, Marcio Almeida, Xiao Qing Liu, and Julia N. Bailey

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A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants, Lars G. Fritsche, Wilmar Igl, Jessica N. Cooke Bailey, Felix Grassmann, Sebanti Sengupta, Jennifer L. Bragg-Gresham, Kathryn P. Burdon, Scott J. Hebbring, Matthew P. Johnson, and John Blangero

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The genetic architecture of type 2 diabetes, Christian Fuchsberger, Jason Flannick, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton, Joanne E. Curran, Satish Kumar, John Blangero, and Ravi Duggirala

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Multidimensional heritability analysis of neuroanatomical shape, Tian Ge, Martin Reuter, Anderson M. Winkler, Avram J. Holmes, Phil H. Lee, Lee S. Tirrell, Joshua L. Roffman, Randy L. Buckner, Jordan W. Smoller, and Mert R. Sabuncu

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The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3, Robert L. Hanson, Fatjon Leti, Darwin Tsinajinnie, Sayuko Kobes, Sobha Puppala, Joanne E. Curran, Laura Almasy, Donna M. Lehman, John Blangero, Ravi Duggirala, and Johanna K. DiStefano

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The integration of quantitative genetics, paleontology, and neontology reveals genetic underpinnings of primate dental evolution, Leslea J. Hlusko, Christopher A. Schmitt, Tesla A. Monson, Marianne F. Brasil, and Michael Mahaney

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Genome-wide significant loci for addiction and anxiety, Karen Hodgson, Laura Almasy, Emma E. M. Knowles, Jack W. Kent Jr., Joanne E. Curran, Thomas D. Dyer, Harald H. H. Goring, Rene L. Olvera, Peter T. Fox, Godfrey D. Pearlson, J. H. Krystal, Ravindranath Duggirala, John Blangero, and David C. Glahn

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Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index, Karen Hodgson, Russell A. Poldrack, Joanne E. Curran, Emma Knowles, Samuel R. Mathias, Harald H. H. Goring, Rene L. Olvera, Peter T. Fox, Laura Almasy, Ravi Duggirala, and John Blangero

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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms, Momoko Horikoshi, Lorenzo Pasquali, Steven Wiltshire, Jeroen R. Huyghe, Anubha Mahajan, Jennifer L. Asimit, and John Blangero

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Preeclampsia does not share common risk alleles in 9p21 with coronary artery disease and type 2 diabetes, Tea Kaartokallio, A. Inkeri LokkiM, Hanna Peterson, Katja Kivinen, Leena Hiltunen, Elina Salmela, Tuuli Lappalainen, Paula Maanselkä, Sanna Heino, and Matthew P. Johnson

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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels, Tuomas O. Kilpeläinen, Jayne F.Martin Carli, Alicja A. Skowronski, Qi Sun, Jennifer Kriebel, Mary F. Feitosa, Åsa K. Hedman, Alexander W. Drong, James E. Hayes, and John Blangero

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Physical activity and FTO genotype by physical activity interactive influences on obesity, Joon Young Kim, Jacob T. DeMenna, Sobha Puppala, Geetha Chittoor, Jennifer Schneider, Ravindranath Duggirala, Lawrence J. Mandarino, Gabriel Q. Shaibi, and Dawn K. Coletta

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Genome-wide Linkage on Chromosome 10q26 for a Dimensional Scale of Major Depression, Emma E. M. Knowles, Jack W. Kent Jr., D. Reese McKay, Emma Sprooten, Samuel R. Mathias, Joanne E. Curran, Melanie A. Carless, Marcio A.A. de Almeida, Harald H. H. Goring, Thomas D. Dyer, Rene L. Olvera, Peter T. Fox, Ravindranath Duggirala, Laura Almasy, John Blangero, and David C. Glahn

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Heterochronicity of white matter development and aging explains regional patient control differences in schizophrenia, Peter Kochunov, Habib Ganjgahi, Anderson M. Winkler, Sinead Kelly, Dinesh Shukla, Xiaoming Du, Neda Jahanshad, Laura Rowland, Hemalatha Sampath, and Binish Patel

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The common genetic influence over processing speed and white matter microstructure: Evidence from the Old Order Amish and Human Connectome Projects, Peter Kochunov, Paul M. Thompson, Anderson M. Winkler, Mary Morrissey, Mao Fu, Thomas R. Coyle, Xiaoming Du, Florian Muellerklein, Anya Savransky, and Christopher Gaudiot

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Soluble Forms of Intercellular and Vascular Cell Adhesion Molecules Independently Predict Progression to Type 2 Diabetes in Mexican American Families, Hemant Kulkarni, Manju Mamtani, Juan M. Peralta, Marcio Almeida, Thomas D. Dyer, Harald H. H. Goring, Matthew P. Johnson, Ravindranath Duggirala, Michael C. Mahaney, Rene L. Olvera, Laura Almasy, David C. Glahn, Sarah Williams-Blangero, Joanne E. Curran, and John Blangero

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Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families, Hemant Kulkarni, Manju Mamtani, Juan M. Peralta, Vincent P. Diego, Thomas D. Dyer, Harald H. H. Goring, Laura Almasy, Sarah Williams-Blangero, Michael C. Mahaney, Ravindranath Duggirala, Joanne E. Curran, and John Blangero

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Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation, Satish Kumar, Joanne E. Curran, David C. Glahn, and John Blangero

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Progressive Bidirectional Age-Related Changes in Default Mode Network Effective Connectivity across Six Decades, Karl Li, Angela R. Laird, Larry R. Price, D. Reese McKay, John Blangero, David C. Glahn, and Peter T. Fox

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk, Yingchang Lu, Felix R. Day, Stefan Gustafsson, Martin L. Buchkovich, Jianbo Na, Veronique Bataille, Diana L. Cousminer, Zari Dastani, Joanne E. Curran, and John Blangero

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Association of Urinary Phthalates with Self-Reported Eye Affliction/Retinopathy in Individuals with Diabetes: National Health and Nutrition Examination Survey, 2001-2010, Manju Mamtani, Joanne E. Curran, John Blangero, and Hemant Kulkarni

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Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families, Manju Mamtani, Hemant Kulkarni, Thomas D. Dyer, Harald H. H. Goring, Jennifer L. Neary, Shelley A. Cole, Jack W. Kent Jr., Satish Kumar, David C. Glahn, Michael C. Mahaney, Anthony G. Comuzzie, Laura Almasy, Joanne E. Curran, Ravindranath Duggirala, John Blangero, and Melanie A. Carless

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Lipidomic risk score independently and cost-effectively predicts risk of future type 2 diabetes: results from diverse cohorts, Manju Mamtani, Hemant Kulkarni, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, David C. Glahn, Sarah Williams-Blangero, Ravindranath Duggirala, John Blangero, and Joanne E. Curran

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The effects of resistance exercise and oral nutritional supplementation during hemodialysis on indicators of nutritional status and quality of life, Geovana Martin-Alemañy, Rafael Valdez-Ortiz, Guadalupe Olvera-Soto, Irma Gomez-Guerrero, Guillermo Aguire-Esquivel, Guillermo Cantu-Quintanilla, Juan Carlos Lopez Alvarenga, Paola Miranda-Alatriste, and Angeles Espinosa-Cuevas

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Recurrent major depression and right hippocampal volume: A bivariate linkage and association study, Samuel R. Mathias, Emma Knowles, Jack W. Kent Jr., D. Reese McKay, Joanne E. Curran, Marcio Almeida, Thomas D. Dyer, Harald H. H. Goring, Rene L. Olvera, Ravi Duggirala, Peter T. Fox, Laura Almasy, John Blangero, and David C. Glahn

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Constrained multivariate association with longitudinal phenotypes, Phillip E. Melton, Juan M. Peralta, and Laura Almasy

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Prosaposin is a regulator of progranulin levels and oligomerization, Alexandra M. Nicholson, NiCole A. Finch, Marcio Almeida, Ralph B. Perkerson, Marka van Blitterswijk, Aleksandra Wojtas, Basar Cenik, Laura Almasy, Thomas D. Dyer, Juan M. Peralta, Joanne E. Curran, Donna M. Lehman, Ravindranath Duggirala, and John Blangero

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Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test, Juan M. Peralta, Marcio A. Almeida, Lawrence J. Abraham, Eric K. Moses, and John Blangero

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Evolution of the Genotype-to-Phenotype Map and the Cost of Pleiotropy in Mammals, Arthur Porto, Ryan Schmelter, John L. VandeBerg, Gabriel Marroig, and James M. Cheverud

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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape, Janina S. Ried, Janina Jeff M., Audrey Y. Chu, Jennifer L. Bragg-Gresham, Jennifer E. Huffman, Tarunveer S. Ahluwalia, Gemma Cadby, Niina Eklund, and John Blangero

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Phenotypic Features of Circulating Leukocytes from Non-human Primates Naturally Infected with Trypanosoma cruzi Resemble the Major Immunological Findings Observed in Human Chagas Disease, Renato Sathler-Avelar, Danielle Marquete Vitelli-Avelar, Armanda Moreira Mattoso-Barbosa, Marcelo Perdigão-de-Oliveira, Ronaldo Peres Costa, Silvana Maria Elói-Santos, Matheus de Souza Gomes, Laurence Rodrigues do Amaral, Jane F. VandeBerg, and John L. VandeBerg

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Serum Vitamin D Concentrations in Baboons (Papio spp.) during Pregnancy and Obesity, Natalia E. Schlabritz-Loutsevitch, Anthony G. Comuzzie, Michael Mahaney, Gene B. Hubbard, Edward J. Dick Jr, Mehmet Kocak, Sonali Gupta, Maira Carrillo, Mauro Schenone, Arnold Postlethwaite, and Andrzej Slominski

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Investigation of Genetic Variation Underlying Central Obesity amongst South Asians, William R. Scott, Weihua Zhang, Marie Loh, Sian-Tsung Tan, Benjamin Lehne, Uzma Azfal, Juan M. Peralta, Richa Saxena, Sarju Ralhan, and Gurpreet S. Wander

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A comprehensive tractography study of patients with bipolar disorder and their unaffected siblings, Emma Sprooten, Jennifer Barrett, D Reese McKay, Emma E. Knowles, Samuel R. Mathias, Anderson M. Winkler, Margaret S. Brumbaugh, Stefanie Landau, Lindsay Cyr, Peter Kochunov, and David C. Glahn

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Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat, Yun Ju Sung, L. Pérusse, M. A. Sarzynski, M. Fornage, S. Sidney, B. Sternfeld, T. Rice, J. G. Terry, D. R. Jacobs Jr., John Blangero, and Joanne E. Curran

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Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families, Farook Thameem, Sobha Puppala, Vidya S. Farook, Balakuntalam S. Kasinath, John Blangero, Ravi Duggirala, and Hanna E. Abboud

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Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression, Michael Traurig, Robert L. Hanson, Alejandra Marinelarena, Sayuko Kobes, Paolo Piaggi, Shelley A. Cole, Joanne E. Curran, John Blangero, Harald H. H. Goring, and Satish Kumar

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Quantitative physical activity assessment of children and adolescents in a rural population from Eastern Nepal, Kimberly D. Williams, Janardan Subedi, Bharat Jha, John Blangero, Sarah Williams-Blangero, and Bradford Towne

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Faster permutation inference in brain imaging, Anderson M. Winkler, Gerard R. Ridgway, Gwenaëlle Douaud, Thomas E. Nichols, and Stephen M. Smith

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Non-parametric combination and related permutation tests for neuroimaging, Anderson M. Winkler, Matthew A. Webster, Jonathan C. Brooks, Irene Tracey, Stephen M. Smith, and Thomas E. Nichols

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Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for PAPSS2 as a Longevity Gene, Laura M. Yerges-Armstrong, Sumbul Chai, Jeffery R. O'Connell, Joanne E. Curran, John Blangero, Braxton D. Mitchell, Alan R. Shuldiner, and Coleen M. Damcott

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Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis, Yuan Zhou, Gu Zhu, Jac C. Charlesworth, Steve Simpson Jr, Rohina Rubicz, Harald H. H. Goring, Nikolaos A. Patsopoulos, John Blangero, Joanne E. Curran, and Matthew P. Johnson

Submissions from 2015

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Nigella sativa influences GLUT4 through the AMPK pathway, Daniel Acevedo, Erika Varela, Juan Guerra, Jameela Banu, and Sara M. Reyna

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Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance-use disorders performing a go/no-go task, Ashley Acheson, Malle A. Tagamets, Anderson M. Winkler, Laura M. Rowland, Charles W. Mathias, Susan N. Wright, L. Elliot Hong, Peter Kochunov, and Donald M. Dougherty

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An epigenetic map of age-associated autosomal loci in northern european families at high risk for the metabolic syndrome, Omar Ali, Diana Cerjak, Jack W. Kent, Roland James, John Blangero, Melanie A. Carless, and Yi Zhang

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Linkage mapping: Localizing the genes that shape human variation, Laura Almasy, Mark Z. Kos, and John Blangero

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Genetic Variants Influencing Joint Damage in Mexican Americans and European Americans With Rheumatoid Arthritis, Rector Arya, Inmaculada Del Rincon, Vidya S. Farook, Jose F. Restrepo, Marcio Almeida, Satish Kumar, Joanne E. Curran, Christopher Jenkinson, John Blangero, Ravi Duggirala, and Agustin Escalante

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Mapping of susceptibility genes for obesity, type 2 diabetes, and the metabolic syndrome in human populations, Rector Arya, Sobha Puppala, Vidya S. Farook, Geetha Chittoor, Christopher P. Jenkinson, John Blangero, Daniel E. Hale, Ravindranath Duggirala, and Laura Almasy

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Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio), Elizabeth G. Atkinson, Jeffrey Rogers, Michael Mahaney, Laura Cox, and James M. Cheverud

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Serum bilirubin concentration is modified by UGT1A1 Haplotypes and influences risk of Type-2 diabetes in the Norfolk Island genetic isolate, M. C. Benton, R. A. Lea, D. Macartney-Coxson, C. Bellis, M. A. Carless, Joanne E. Curran, D. Eccles, G. K. Chambers, John Blangero, and L. R. Griffiths

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A Phenomic Scan of the Norfolk Island Genetic Isolate Identifies a Major Pleiotropic Effect Locus Associated with Metabolic and Renal Disorder Markers, Miles C. Benton, Rodney A. Lea, Donia Macartney-Coxson, Michelle Hanna, David A. Eccles, Melanie A. Carless, Claire Bellis, Harald H. H. Goring, Joanne E. Curran, and John Blangero

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'Mutiny on the Bounty': the genetic history of Norfolk Island reveals extreme gender-biased admixture, Miles C. Benton, Shani Stuart, Claire Bellis, Donia Macartney-Coxson, David Eccles, Joanne E. Curran, Geoff Chambers, John Blangero, Rod A. Lea, and L. R. Griffiths

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Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans, August Blackburn, Marcio A. Almeida, Angela Dean, Joanne E. Curran, Matthew P. Johnson, Thomas D. Dyer, Michael Mahaney, Sarah Williams-Blangero, John Blangero, and Harald H. H. Goring

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A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study, Nicholas B. Blackburn, Jac C. Charlesworth, James R. Marthick, Elizabeth M. Tegg, Katherine A. Marsden, Velandai Srikanth, John Blangero, Ray M. Lowenthal, Simon J. Foote, and Joanne L. Dickinson

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Genomic studies of human populations: Resequencing approaches to the identification of human quantitative loci, Joanne E. Curran, Claire Bellis, Laura Almasy, and John Blangero

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Shared genetic factors influence amygdala volumes and risk for alcoholism, Alecia D. Dager, D. Reese McKay, Jack W. Kent, Joanne E. Curran, Emma Knowles, Emma Sprooten, Harald H.H. Göring, Thomas D. Dyer, Rene L. Olvera, and John Blangero

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Interaction of brain areas of visual and vestibular simultaneous activity with fMRI, Hellen M. Della-Justina, Humberto R. Gamba, Katerina Lukasova, Mariana P. Nucci-da-Silva, Anderson M. Winkler, and Edson Amaro Jr

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Sex-specific genetic effects in physical activity: results from a quantitative genetic analysis, Vincent P. Diego, Raquel Nichele de Chaves, John Blangero, Daniel Santos, Thayse Natacha Gomes, Fernanda Karina dos Santos, Rui Garganta, Peter T. Katzmarzyk, and José AR Maia

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Fatty acids linked to cardiovascular mortality are associated with risk factors, Sven O. E. Ebbesson, V. Saroja Voruganti, Paul B. Higgins, Richard R. Fabsitz, Lars O. Ebbesson, Sandra Laston, William S. Harris, John Kennish, Benjamin D. Umans, and Hong Wang

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Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children, V. S. Farook, L. Reddivari, G. Chittoor, S. Puppala, Rector Arya, S. P. Fowler, Joanne E. Curran, John Blangero, and Ravi Duggirala

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Intergenerational neural mediators of early-life anxious temperament, Andrew S. Fox, Jonathan A. Oler, Alexander J. Shackman, Steven E. Shelton, Muthuswamy Raveendran, D. Reese McKay, Alexander K. Converse, Andrew Alexander, Richard J. Davidson, and John Blangero

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Fast and powerful heritability inference for family-based neuroimaging studies, Habib Ganjgahi, Anderson M. Winkler, David C. Glahn, John Blangero, Peter Kochunov, and Thomas E. Nichols

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Discovering schizophrenia endophenotypes in randomly ascertained pedigrees, David C. Glahn, Jeff T. Williams, Joanne E. Curran, Harald H. H. Goring, Thomas D. Dyer, Anderson M. Winkler, Rene L. Olvera, Ravi Duggirala, Laura Almasy, and John Blangero

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Novel loci associated with usual sleep duration: The CHARGE Consortium Genome-Wide Association Study, D. J. Gottlieb, K. Hek, T. H. Chen, N. F. Watson, G. Eiriksdottir, E. M. Byrne, M. Cornelis, S. C. Warby, S. Bandinelli, and John Blangero

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Linkage Analysis of Urine Arsenic Species Patterns in the Strong Heart Family Study, Matthew O. Gribble, Venkata Saroja Voruganti, Shelley A. Cole, Karin Haack, Poojitha Balakrishnan, Sandra Laston, Maria Tellez-Plaza, Kevin A. Francesconi, Walter Goessler, and Jason G. Umans

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Common genetic variants influence human subcortical brain structures, Derrek P. Hibar, Jason L. Stein, Miguel E. Renteria, Alejandro Arias-Vasquez, John Blangero, Anderson M. Winkler, Joanne E. Curran, Thomas D. Dyer, Peter T. Fox, and Ravi Duggirala

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Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits, Yu S. Huang, Vasily Ramensky, Susan K. Service, Anna J. Jasinska, Yoon Jung, Oi-Wa Choi, Rita M. Cantor, Thomas D. Dyer, and John Blangero

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Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype, Christopher Jenkinson, Harald H. H. Goring, Rector Arya, John Blangero, Ravindranath Duggirala, and Ralph A. DeFronzo

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Genetic influences on response to novel objects and dimensions of personality in Papio baboons, Zachary Johnson, Linda Brent, Juan Carlos Lopez Alvarenga, Anthony G. Comuzzie, Wendy Shelledy, Stephanie Ramirez, Laura Cox, Michael C. Mahaney, Yung-Yu Huang, and John Mann

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A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data, Young Jin Kim, Taesung Park, Gonçalo Abecasis, Marcio A. Almeida, David Altshuler, Jennifer L. Asimit, Gil Atzmon, Mathew Barber, John Blangero, and Thomas D. Dyer

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Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage, Emma E.M. Knowles, Reese McKay, Jack W. Kent, Emma Sprooten, Melanie A. Carless, Joanne E. Curran, Marcio A. Almeida, Thomas D. Dyer, Harald H.H. Göring, Ravi Duggirala, and John Blangero

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Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data, Peter Kochunov, Neda Jahanshad, Daniel Marcus, Anderson M. Winkler, Laura Almasy, Joanne E. Curran, Ravi Duggirala, Peter T. Fox, Rene L. Olvera, and John Blangero

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Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk, Mark Kos, Melanie A. Carless, Juan M. Peralta, August N. Blackburn, Marcio Almeida, David Roalf, Michael F. Pogue-Geile, Joanne E. Curran, Ravi Duggirala, John Blangero, and Laura Almasy

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Novel epigenetic determinants of type 2 diabetes in Mexican-American families, Hemant Kulkarni, Mark Kos, Jennifer L. Neary, Thomas D. Dyer, Jack W. Kent Jr., Harald H. H. Goring, Shelley A. Cole, Anthony G. Comuzzie, Laura Almasy, Michael Mahaney, Joanne E. Curran, John Blangero, and Carles Badenes

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Genetics of kidney disease and related cardiometabolic phenotypes in Zuni Indians: the Zuni Kidney Project, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Vallabh O. Shah, Arlene Bobelu, Jeanette Bobelu, Donica Ghahate, Antonia M. Harford, Susan S. Paine, and Francesca Tentori

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Genetic studies of body mass index yield new insights for obesity biology, A. E. Locke, B. Kahali, S. I. Berndt, A. E. Justice, T. H. Pers, F. R. Day, C. Powell, S. Vedantam, M. L. Buchkovich, and John Blangero

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Genetics of cardiovascular disease in minority populations, Jean W. MacCluer, John Blangero, Anthony G. Comuzzie, Sven O.E. Ebbesson, Barbara V. Howard, and Shelley A. Cole

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Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus, Anubha Mahajan, Xueling Sim, Hui Jin Ng, Alisa Manning, Manuel A. Rivas, Heather M. Highland, Adam E. Locke, Niels Grarup, Hae Kyung Im, John Blangero, and Joanne E. Curran

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Genetic Influence on the Human Brain, D Reese McKay, Anderson M. Winkler, Peter Kochunov, Emma E. M. Knowles, Emma Sprooten, Peter T. Fox, John Blangero, and David C. Glahn

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Statin action favors normalization of the plasma lipidome in the atherogenic mixed dyslipidemia of MetS: Potential relevance to statin-associated dysglycemia, Peter J. Meikle, Gerard Wong, Ricardo Tan, Philippe Giral, Paul Robillard, Alexina Orsoni, Neil Hounslow, Dianna J. Magliano, Jonathan E. Shaw, Joanne E. Curran, and John Blangero

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The transcriptional landscape of age in human peripheral blood, Marjolein J. Peters, Roby Joehanes, Luke C. Pilling, Claudia Schurmann, Karen N. Conneely, Harald H. H. Goring, Joanne E. Curran, Sarah Williams-Blangero, and John Blangero

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Long-term neural and physiological phenotyping of a single human, Russell A. Poldrack, Timothy O. Laumann, Oluwasanmi Koyejo, Brenda Gregory, Ashleigh Hover, Mei-Yen Chen, Krzysztof J. Gorgolewski, Joanne E. Curran, Harald H. H. Goring, and John Blangero