Human Genetics Publications and Presentations
Submissions from 2022
Keeping 21st Century Paleontology Grounded: Quantitative Genetic Analyses and Ancestral State Reconstruction Re-Emphasize the Essentiality of Fossils, Tesla A. Monson, Marianne F. Brasil, Michael Mahaney, Christopher A. Schmitt, Catherine E. Taylor, and Leslea J. Hlusko
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors, Niamh Mullins, Joo Eun Kang, Adrian I. Campos, Jonathan R.I. Coleman, and Ney Alliey Rodriguez
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential, Tetsushi Nakao, Alexander G. Bick, Margaret A. Taub, Seyedeh M. Zekavat, Md M. Uddin, Abhishek Niroula, Juan M. Peralta, Joanne E. Curran, and John Blangero
tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel, Tulika Nandi, Oula Puonti, William T. Clarke, Caroline Nettekoven, Helen C. Barron, James Kolasinski, Taylor Hanayik, Emily L. Hinson, Adam Berrington, and Anderson M. Winkler
The Nonsynonymous-Single-Nucleotide Polymorphism (ns-SNP) 353 R>q in the Coagulation Factor VII (FVII) Gene, F7, is Associated with Decreased Plasma FVII Levels and a Decreased Risk of Coronary Heart Disease (CHD) in Mexican Americans of South Texas, Kanisha Patel, Vincent P. Diego, Alberto D. Lopez, Marcio Almeida, Joanne E. Curran, Miguel A. Escobar, Jerry S. Powell, Donna M. Lehman, Ralph A. DeFronzo, Sarah Williams-Blangero, Ravi Duggirala, Laura Almasy, John Blangero, and Tom Howard
Hepatic transcript signatures predict atherosclerotic lesion burden prior to a 2-year high cholesterol, high fat diet challenge, Sobha Puppala, Kimberly D. Spradling-Reeves, Jeannie Chan, Shifra Birnbaum, Deborah E. Newman, Anthony G. Comuzzie, Michael Mahaney, John L. VandeBerg, Michael Olivier, and Laura Cox
Differential Role of Type 2 Diabetes as a Risk Factor for Tuberculosis in the Elderly versus Younger Adults, Blanca I. Restrepo, Julia M. Scordo, Genesis P. Aguillón-Durán, Doris Ayala, Ana P. Quirino-Cerrillo, Raúl Loera-Salazar, America Cruz-González, Jose A. Caso, Mateo Joya-Ayala, Esperanza M. García-Oropesa, and Alejandra B. Salinas
Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study, Nadine Saul, Ineke Dhondt, Mikko Kuokkanen, Markus Perola, Clara Verschuuren, Brecht Wouters, Henrik von Chrzanowski, Winnok H. De Vos, Liesbet Temmerman, and Walter Luyten
Whole genome sequence analysis of blood lipid levels in >66,000 individuals, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Akhil Pampana, David Y. Zhang, Joanne E. Curran, Ravi Duggirala, John Blangero, Juan M. Peralta, Harald HH Goring, and Michael Mahaney
Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis, Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, and Shu-Hsia Chen
Multi-OMICs analysis reveals metabolic and epigenetic changes associated with macrophage polarization, Mark L. Sowers, Hui Tang, Vipul K. Singh, Arshad Khan, Abhishek Mishra, Blanca I. Restrepo, Chinnaswamy Jagannath, and Kangling Zhang
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals, Usman A. Tahir, Daniel H. Katz, Julian Avila-Pachecho, Alexander G. Bick, Akhil Pampana, Jeremy M. Robbins, Zhi Yu, Zsu-Zsu Chen, Mark D. Benson, and John Blangero
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed, Margaret A. Taub, Matthew P. Conomos, Rebecca Keener, Kruthika R. Iyer, Joshua S. Weinstock, Lisa R. Yanek, John Lane, John Blangero, Joanne E. Curran, and Juan M. Peralta
The Enhancing NeuroImaging Genetics through Meta-Analysis Consortium: 10 Years of Global Collaborations in Human Brain Mapping, Paul M. Thompson, Neda Jahanshad, Lianne Schmaal, Jessica A. Turner, Anderson M. Winkler, Sophia I. Thomopoulos, Gary F. Egan, and Peter Kochunov
The Impact of Aging on the Lung Alveolar Environment, Predetermining Susceptibility to Respiratory Infections, Jordi B. Torrelles, Blanca I. Restrepo, Yidong Bai, Corinna Ross, Larry S. Schlesinger, and Joanne Turner
Burden of Type 2 Diabetes and Associated Cardiometabolic Traits and Their Heritability Estimates in Endogamous Ethnic Groups of India: Findings From the INDIGENIUS Consortium, Vettriselvi Venkatesan, Rector Arya, Juan Carlos Lopez Alvarenga, Krishna K. Sharma, Roy G. Resendez, Juliet A. Ezeilo, Marcio Almeida, Srinivas Mummidi, John Blangero, and Ravindranath Duggirala
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data, Pierrick Wainschtein, Deepti Jain, Zhili Zheng, Stella Aslibekyan, Diane Becker, Wenjian Bi, Jennifer Brody, Jenna C. Carlson, Adolfo Correa, and John Blangero
The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations, Zhe Wang, Shing Wan Choi, Nathalie Chami, Eric Boerwinkle, Myriam Fornage, Susan Redline, Joshua C. Bis, Jennifer A. Brody, Bruce M. Psaty, and John Blangero
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention, Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Tim Moore, Daiane Hemerich, Marilyn C. Cornelis, Eugenia Mazzaferro, Siacia Broos, Tarunveer S. Ahluwalia, and John Blangero
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program, Marsha M. Wheeler, Adrienne M. Stilp, Shuquan Rao, Bjarni V. Halldórsson, Doruk Beyter, Jia Wen, Anna V. Mihkaylova, Laura Almasy, John Blangero, and Joanne E. Curran
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals, Thomas W. Winkler, Humaira Rasheed, Alexander Teumer, Mathias Gorski, Bryce X. Rowan, Kira J. Stanzick, Laurent F. Thomas, Adrienne Tin, Anselm Hoppmann, and Mikko Kuokkanen
Genetic and genomic architecture in eight strains of the laboratory opossum Monodelphis domestica, Xiao Xiong, Paul B. Samollow, Wenqi Cao, Richard Metz, Chao Zhang, Ana C. Leandro, John L. VandeBerg, and Xu Wang
Tuberculosis Phenotypic and Genotypic Drug Susceptibility Testing and Immunodiagnostics: A Review, Kizil A. Yusoof, Juan Ignacio Garcia, Alyssa Schami, Andreu Garcia-Vilanova, Holden V. Kelley, Shu-Hua Wang, Adrian Rendon, Blanca I. Restrepo, Marcel Yotebieng, and Jordi B. Torrelles
Lipidomic profiling in the Strong Heart Study identified American Indians at risk of chronic kidney disease, Wenjie Zeng, Habtamu B. Beyene, Mikko Kuokkanen, Guanhong Miao, Dianna J. Magliano, Jason G. Umans, Nora Franceschini, Joanne E. Curran, and John Blangero
Shared brain and genetic architectures between mental health and physical activity, Wei Zhang, Sarah E. Paul, Anderson M. Winkler, Ryan Bogdan, and Janine D. Bijsterbosch
Mega‐analysis methods in ENIGMA: The experience of the generalized anxiety disorder working group, André Zugman, Anita Harrewijn, Elise M. Cardinale, Hannah Zwiebel, Gabrielle F. Freitag, Katy E. Werwath, Janna Marie Bas-Hoogendam, Nynke A. Groenewold, Moji Aghajani, and Anderson M. Winkler
Submissions from 2021
COVID-19 and chronic diabetes: the perfect storm for reactivation tuberculosis?: a case series, Genesis P. Aguillón-Durán, Ericka Prieto-Martinez Dr, Doris Ayala, Juan García Jr., John M. Thomas III, Juan Ignacio García, Brandon Michael Henry, Jordi B. Torrelles, Joanne Turner, Eder Ledezma-Campos, and Blanca I. Restrepo
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders, Till F.M. Andlauer, Jose Guzman-Parra, Fabian Streit, Jana Strohmaier, and Ney Alliey Rodriguez
Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness, Annayya R. Aroor, Srinivas Mummidi, Juan C. Lopez-Alvarenga, Nitin Das, Javad Habibi, Guanghong Jia, Guido Lastra, and Bysani Chandrasekar
Neuroimaging Association Scores: reliability and validity of aggregate measures of brain structural features linked to mental disorders in youth, Luiza Kvitko Axelrud, André Rafael Simioni, Daniel Samuel Pine, Anderson M. Winkler, Pedro Mario Pan, João Ricardo Sato, André Zugman, Nadine Parker, Felipe Picon, and Andrea Jackowski
Transcriptomic Profiling of Fibropapillomatosis in Green Sea Turtles (Chelonia mydas) From South Texas, Nicholas B. Blackburn, Ana C. Leandro, Nina Nahvi, Mariana A. Devlin, Marcelo Leandro, Ignacio Martinez Escobedo, Juan M. Peralta, Jeff George, Thomas W. deMaar, John Blangero, Megan Keniry, and Joanne E. Curran
Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3, Nicholas B. Blackburn, Peter J. Meikle, Juan M. Peralta, Satish Kumar, Ana C. Leandro, Melissa A. Bellinger, Michael Mahaney, Harald H. H. Goring, John L. VandeBerg, Sarah Williams-Blangero, David C. Glahn, Ravi Duggirala, John Blangero, and Joanne E. Curran
Genz and Mendell-Elston Estimation of the High-Dimensional Multivariate Normal Distribution, Lucy Blondell, Mark Kos, John Blangero, and Harald H. H. Goring
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program, Brian E. Cade, Brian E. Cade, Jiwon Lee, Tamar Sofer, Heming Wang, Man Zhang, Han Chen, John Blangero, Joanne E. Curran, and Juan M. Peralta
Total Plasma Homocysteine and Depressive Symptoms in Older Hispanics, Fernando Castro, Jesus D. Melgarejo, Carlos A. Chavez, Gabriel A. de Erausquin, Joseph D. Terwilliger, Joseph H. Lee, and Gladys E. Maestre
Nanotechnology Synergised Immunoengineering for Cancer, Deepak S. Chauhan, Anupam Dhasmana, Partha Laskar, Rajendra Prasad, Nishant K. Jain, Rohit Srivastava, Meena Jaggi, Subhash C. Chauhan, and Murali M. Yallapu
Anterior-posterior axis of hippocampal subfields across psychoses: A B-SNIP study, Elisabetta C. del Re, Victor Zeng, Ney Alliey-Rodriguez, Paulo Lizano, and Nicolas Bolo
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders, Seenae Eum, S. Kristian Hill, Ney Alliey Rodriguez, James M. Stevenson, and Leah H. Rubin
Allocentric representation in the human amygdala and ventral visual stream, Hallvard Røe Evensmoen, Lars M. Rimol, Anderson M. Winkler, Richard Betzel, and Tor Ivar Hansen
Amygdala Functional Connectivity and Negative Reactive Temperament at Age 4 Months, Courtney A. Filippi, Sanjana Ravi, Maya Bracy, Anderson M. Winkler, Chad Sylvester, Daniel Samuel Pine, and Nathan A. Fox
Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project, Si Gao, Brian Donohue, Kathryn S. Hatch, Shuo Chen, Tianzhou Ma, Yizhou Ma, Mark D. Kvarta, Bhim M. Adhikari, Neda Jahanshad, and John Blangero
New Developments and Insights in the Improvement of Mycobacterium tuberculosis Vaccines and Diagnostics Within the End TB Strategy, Juan Ignacio García, Anna Allué-Guardia, Radhika P. Tampi, Blanca I. Restrepo, and Jordi B. Torrelles
Neuropsychiatric Symptoms Among Hispanics: Results of the Maracaibo Aging Study, Mario Gil, Ney Alliey-Rodriguez, Juan Carlos Lopez Alvarenga, Vincent P. Diego, Ciro Gaona, Ledys Mata, Rosa V. Pirela, Carlos A. Chavez, Gabriel A. de Erausquin, Jesus D. Melgarejo, and Gladys E. Maestre
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes, Julia K. Goodrich, Moriel Singer-Berk, Rachel Son, Abigail Sveden, Jordan Wood, Eleina England, Joanne B. Cole, John Blangero, Ben Weisburd, and Ravi Duggirala
APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups, Shiwali Goyal, Yosuke Tanigawa, Weihua Zhang, Jin-Fang Chai, Marcio Almeida, Juan M. Peralta, Donna M. Lehman, Joanne E. Curran, Ravi Duggirala, and John Blangero
Increasing Public Health Mosquito Surveillance in Hidalgo County, Texas to Monitor Vector and Arboviral Presence, Clarissa D. Guerrero, Steven Hinojosa, Diana Vanegas, Niko Tapangan, Matthew Guajardo, Sara Alaniz, Narda Cano, Christopher Vitek, John M. Thomas, Valerie Hernandez, and Juan Garcia Jr.
Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group, Anita Harrewijn, Elise M. Cardinale, Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Moji Aghajani, Kevin Hilbert, Narcis Cardoner, Daniel Porta-Casteràs, Savannah Gosnell, and Anderson M. Winkler
Comparing neural correlates of conditioned inhibition between children with and without anxiety disorders - A preliminary study, Anita Harrewijn, Elizabeth R. Kitt, Rany Abend, Chika Matsumoto, Paola Odriozola, Anderson M. Winkler, Ellen Leibenluft, Daniel S. Pine, and Dylan G. Gee
LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance, Sijia He, Jiyoon Ryu, Juanhong Liu, Hairong Luo, Ying Lv, Paul R. Langlais, Jie Wen, Feng Dong, Zhe Sun, and Ravindranath Duggirala
Genetic variants and physical activity interact to affect bone density in Hispanic children, Ruixue Hou, Shelley A. Cole, Mariaelisa Griff, Yujie Wang, Karin Haack, Sandra Laston, Nitesh R. Mehta, Roman J. Shypailo, Margaret L. Gourlay, and Anthony G. Comuzzie
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program, Yao Hu, Adrienne M. Stilp, Caitlin McHugh, Shuquan Rao, Deepti Jain, Xiuwen Zheng, John Lane, Ravi Duggirala, Joanne E. Curran, and John Blangero
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium, Silva Kasela, Victor E. Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, John Blangero, Joanne E. Curran, and Juan M. Peralta
Genome sequencing unveils a regulatory landscape of platelet reactivity, Ali R. Keramati, Ming-Huei Chen, Lisa R. Yanek, Arunoday Bhan, John Blangero, Benjamin A. T. Rodriguez, Joanne E. Curran, Michael Mahaney, Harald HH Goring, and Ravi Duggirala
Genetic Overlap Profiles of Cognitive Ability in Psychotic and Affective Illnesses: A Multisite Study of Multiplex Pedigrees, Emma Knowles, Juan M. Peralta, Laura Almasy, Vishwajit Nimgaonkar, Francis J. McMahon, Pippa Thomson, Samuel R. Mathias, Joanne E. Curran, and John Blangero
A White Matter Connection of Schizophrenia and Alzheimer’s Disease, Peter Kochunov, Artemis Zavaliangos-Petropulu, Neda Jahanshad, Paul M. Thompson, Meghann C. Ryan, Joshua Chiappelli, Shuo Chen, Xiaoming Du, Kathryn Hatch, Bhim Adhikari, Joanne E. Curran, and John Blangero
Whole Genome Sequence Data From Captive Baboons Implicate RBFOX1 in Epileptic Seizure Risk, Mark Z. Kos, Melanie A. Carless, Lucy Blondell, M. Michelle Leland, Koyle D. Knape, Harald HH Goring, and Charles A. Szabo
Using the Schmahmann Syndrome Scale to Assess Cognitive Impairment in Young Adults with Metabolic Syndrome: A Hypothesis-Generating Report, Eithan Kotkowski, Larry R. Price, Cheasequah J. Blevins, Crystal Franklin, Mary Woolsey, Ralph A. DeFronzo, John Blangero, Ravindranath Duggirala, David C. Glahn, Jeremy Schmahmann, and Peter T. Fox
Disease Modeling and Disease Gene Discovery in Cardiomyopathies: A Molecular Study of Induced Pluripotent Stem Cell Generated Cardiomyocytes, Satish Kumar, Joanne E. Curran, Kashish Kumar, Erica De Leon, Ana C. Leandro, Juan M. Peralta, Sarah Williams-Blangero, and John Blangero
Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries, Alan M. Kwong, Thomas W. Blackwell, Jonathon LeFaive, Mariza de Andrade, John Barnard, Kathleen C. Barnes, and John Blangero
Reassessing associations between white matter and behaviour with multimodal microstructural imaging, Alberto Lazari, Piergiorgio Salvan, Michiel Cottaar, Daniel Papp, Olof Jens van der Werf, Ainslie Johnstone, Zeena-Britt Sanders, Cassandra Sampaio-Baptista, Nicole Eichert, and Anderson M. Winkler
Shared and anxiety-specific pediatric psychopathology dimensions manifest distributed neural correlates, Julia O. Linke, Rany Abend, Katharina Kircanski, Michal Clayton, Caitlin Stavish, Brenda E. Benson, Melissa A. Brotman, Olivier Renaud, Stephen M. Smith, and Anderson M. Winkler
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction, Richard Karlsson Linnér, Travis T. Mallard, Peter B. Barr, Sandra Sanchez-Roige, James W. Madole, Morgan N. Driver, Holly E. Poore, Ronald de Vlaming, Andrew D. Grotzinger, and Mark Kos
Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study, Yian Lin, Adam X. Maihofer, Emma Stapp, Megan Ritchey, and Ney Alliey Rodriguez
Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative, Amarise Little, Yao Hu, Quan Sun, Deepti Jain, Jai G. Broome, Ming-Huei Chen, Florian Thibord, Caitlin McHugh, John Blangero, and Joanne E. Curran
Association of HIV-1 Infection and Antiretroviral Therapy With Type 2 Diabetes in the Hispanic Population of the Rio Grande Valley, Texas, USA, Juan Carlos Lopez Alvarenga, Dora A. Martinez, Alvaro Diaz-Badillo, Liza D. Morales, Rector Arya, Christopher Jenkinson, Joanne E. Curran, John Blangero, Ravi Duggirala, Srinivas Mummidi, and Ruben D. Martinez
A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response, Yang Luo, Masahiro Kanai, Wanson Choi, Xinyi Li, John Blangero, Joanne E. Curran, Ravi Duggirala, Harald H. H. Goring, Michael C. Mahaney, and Juan M. Peralta
Frailty Index in the Colonias on the US-Mexico Border: A Special Report, Eron G. Manusov, Carolina Gomez De Ziegler, Vincent P. Diego, Gerardo Munoz-Monaco, and Sarah Williams-Blangero
Case Report: Neurologic Presentation of West Nile Virus: Difficult Diagnosis, Eron G. Manusov, Amalia Mora Campuzano, Omar Ahmed, Samantha Macias, Carolina Gomez de Ziegler, and Gerardo Munoz Monaco
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program, Anna V. Mikhaylova, Caitlin P. McHugh, Linda M. Polfus, Laura M. Raffield, Meher Preethi Boorgula, Thomas W. Blackwell, Jennifer A. Brody, Jai Broome, Joanne E. Curran, and John Blangero
Absence of coding somatic single nucleotide variants within well-known candidate genes in late-onset sporadic Alzheimer's Disease based on the analysis of multi-omics data, Shishi Min, Zongchang Li, Annie Shieh, Gina Giase, and Ney Alliey Rodriguez
Genetic influences on externalizing psychopathology overlap with cognitive functioning and show developmental variation, Josephine Mollon, Emma E. M. Knowles, Samuel R. Mathias, Amanda Rodrigue, Tyler M. Moore, Monica E. Calkins, Ruben C. Gur, Juan M. Peralta, Daniel J. Weiner, John Blangero, and Laura Almasy
Genetic influence on cognitive development between childhood and adulthood, Josephine Mollon, Emma Knowles, Samuel R. Mathias, Ruben Gur, Juan M. Peralta, Daniel J. Weiner, Elise B. Robinson, Raquel E. Gur, John Blangero, Laura Almasy, and David C. Glahn
Further evidence supporting a potential role for ADH1B in obesity, Liza D. Morales, Douglas T. Cromack, Devjit Tripathy, Marcel Fourcaudot, Satish Kumar, Joanne E. Curran, Melanie A. Carless, Harald H. H. Goring, Shirley L. Hu, Juan C. Lopez-Alvarenga, Päivi Pajukanta, Kerrin S. Small, Rector Arya, Srinivas Mummidi, John Blangero, Ravindranath Duggirala, and Christopher P. Jenkinson
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology, Niamh Mullins, Andreas J. Forstner, Kevin S. O’Connell, Brandon Coombes, and Ney Alliey Rodriguez
Serum carotenoids and Pediatric Metabolic Index predict insulin sensitivity in Mexican American children, Srinivas Mummidi, Vidya S. Farook, Lavanya Reddivari, Joselin Hernandez-Ruiz, Alvaro Diaz-Badillo, Sharon P. Fowler, Roy G. Resendez, Feroz Akhtar, Donna M. Lehman, Christopher P. Jenkinson, Rector Arya, Jane L. Lynch, Jose A. Canas, Ralph A. DeFronzo, Daniel E. Hale, John Blangero, Juan C. Lopez-Alvarenga, Ravindranath Duggirala, and Jairam K. P. Vanamala
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices, Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni Ruotsalainen, Paul S. de Vries, Jai G. Broome, Juan M. Peralta, John Blangero, Joanne E. Curran, and James P. Pirruccello
Prevalence of dementia in Latin America: a collaborative study of population-based cohorts, Ricardo Nitrini, Cássio M. C. Bottino, Cecilia Albala, Nilton Santos Custodio Capuñay, Carlos Ketzoian, Juan J. Llibre Rodriguez, Gladys E. Maestre, and Ana Teresa A. Ramos-Cerqueira
High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive nonhuman primate breeding colony in Texas, USA, Angel M. Padilla, Phil Y. Yao, Tre J. Landry, Gretchen M. Cooley, Susan M. Mahaney, Isabela Ribeiro, John L. VandeBerg, and Rick L. Tarleton
A Randomized, Controlled Study on the Safety and Efficacy of Maraviroc and/or Favipiravir vs Currently Used Therapy in Severe COVID-19 Adults. “COMVIVIR” Trial., Adolfo Pérez-García, Alma Villalobos-Osnaya, Maria Luisa Hernández-Medel, Lucia Monserrat Perez-Navarro, Elba O. Medina-Hernandez, Diana Soa Cabrera-Orejuela, Ana Maria Espinoza-Garcia, Mireya Leon-Hernandez, Juan Carlos Lopez Alvarenga, and Srinivas Mummidi
Human monocyte-derived macrophage responses to M. tuberculosis differ by the host’s tuberculosis, diabetes or obesity status, and are enhanced by rapamycin, Blanca I. Restrepo, Arshad Khan, Vipul K. Singh, Erica De Leon, Genesis P. Aguillón-Durán, Eder Ledezma-Campos, David H. Canaday, and Chinnaswamy Jagannath
Hyperglycemia and dyslipidemia: Reduced HLA-DR expression in monocyte subpopulations from diabetes patients, Blanca I. Restrepo, Marcel Twahirwa, and Chinnaswamy Jagannath
Genomic variations in patients with myelodysplastic syndrome and karyotypes without numerical or structural changes, Cristiano Luiz Ribeiro, Irene P. Pinto, Samara S. S. Pereira, Lysa B. Minasi, Fernanda de S. M. Kluthcouski, Adriano de M. Arantes, Aparecido D. Cruz, Marcio Almeida, and Tom E. Howard
Searching for Imaging Biomarkers of Psychotic Dysconnectivity, Amanda L. Rodrigue, Dana Mastrovito, Oscar Esteban, Joke Durnez, Marinka M. G. Koenis, Ronald Janssen, Aaron Alexander-Bloch, Emma M. Knowles, Samuel R. Mathias, and John Blangero
Multimodal Imaging Brain Markers in Early Adolescence Are Linked with a Physically Active Lifestyle, Piergiorgio Salvan, Thomas Wassenaar, Catherine Wheatley, Nicholas Beale, Michiel Cottaar, Daniel Papp, Matteo Bastiani, Sean P. Fitzgibbon, Euguene Duff, and Anderson M. Winkler
Phenotypic and Functional Signatures of Peripheral Blood and Spleen Compartments of Cynomolgus Macaques Infected With T. cruzi: Associations With Cardiac Histopathological Characteristics, Renato Sathler-Avelar, Danielle Marquete Vitelli-Avelar, Armanda Moreira Mattoso-Barbosa, Marcelo Antônio Pascoal-Xavier, Silvana Maria Elói-Santos, Ismael Artur da Costa-Rocha, Andréa Teixeira-Carvalho, Edward J. Dick Jr, Jane F. VandeBerg, John L. VandeBerg, and Olindo Assis Martins-Filho
Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people, Julia M. Scordo, Genesis P. Aguillón-Durán, Doris Ayala, Ana Paulina Quirino-Cerrillo, Eminé Rodriguez-Reyna, Mateo Joya-Ayala, Francisco Mora-Guzmán, Eder Ledezma-Campos, Alejandro Villafañez, Larry S. Schlesinger, and Blanca I. Restrepo
A prospective cross-sectional study of tuberculosis in elderly Hispanics reveals that BCG vaccination at birth is protective whereas diabetes is not a risk factor, Julia M. Scordo, Genesis P. Aguillón-Durán, Doris Ayala, Ana P. Quirino-Cerrillo, Eminé Rodriguez-Reyna, Francisco Mora-Guzmán Dr, Jose A. Caso, Eder Ledezma-Campos, Larry Schlesinger, Jordi B. Torrelles, and Blanca I. Restrepo
Population sequencing data reveal a compendium of mutational processes in human germline, Vladimir B. Seplyarskiy, Ruslan A. Soldatov, Evan Koch, Ryan J. McGinty, Jakob M. Goldmann, Ryan D. Hernandez, Kathleen Barnes, Adolfo Correa, Esteban G. Burchard, and John Blangero
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level, Tamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos, Joshua C. Bis, Timothy A. Thornton, Adam Szpiro, Joanne E. Curran, and Michael Mahaney
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans, Ida E. Sønderby, Dennis van der Meer, Clara Moreau, Tobias Kaufmann, G. Bragi Walters, Maria Ellegaard, Nicholas B. Blackburn, John Blangero, Joanne E. Curran, and Juan M. Peralta
The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretion, Sergiy Sukhanov, Yusuke Higashi, Tadashi Yoshida, Srinivas Mummidi, Annayya R. Aroor, Jacob Jeffrey Russell, Shawn B. Bender, Vincent G. DeMarco, and Bysani Chandrasekar
An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in chronic multiple sclerosis and neuromyelitis optica brain lesions and normal appearing brain tissue, George Tackley, Yazhuo Kong, Rachel Minne, Silvia Messina, Anderson M. Winkler, Ana Cavey, Rosie Everett, Gabriele C. DeLuca, Andrew Weir, and Matthew Craner
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program, Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, John Blangero, Joanne E. Curran, Michael C. Mahaney, Harald H. H. Goring, Ravindranath Duggirala, and Juan M. Peralta
Biotyping in psychosis: using multiple computational approaches with one data set, Carol A. Tamminga, Brett A. Clementz, Godfrey Pearlson, Macheri Keshavan, and Ney Alliey Rodriguez
Multi-phenotype genome-wide association studies of the Norfolk Island isolate implicate pleiotropic loci involved in chronic kidney disease, Ngan K. Tran, Rodney A. Lea, Samuel Holland, Quan Nguyen, Arti M. Raghubar, Heidi G. Sutherland, Miles C. Benton, Nicholas B. Blackburn, Joanne E. Curran, and John Blangero
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors, Kelsey Yetsko, Jessica A. Farrell, Nicholas B. Blackburn, Liam Whitmore, Maximilian R. Stammnitz, Jenny Whilde, Catherine B. Eastman, Devon Rollinson Ramia, and Ana C. Leandro
Recent advances in understanding neural correlates of anxiety disorders in children and adolescents, André Zugman, Anderson M. Winkler, and Daniel Samuel Pine
Submissions from 2020
Anticipatory Threat Responding: Associations With Anxiety, Development, and Brain Structure, Rany Abend, Andrea L. Gold, Jennifer C. Britton, Kalina J. Michalska, Tomer Shechner, Jessica F. Sachs, Anderson M. Winkler, and Ellen Leibenluft
Multiple testing correction over contrasts for brain imaging, Bianca A. Alberton, Thomas E. Nichols, Humberto R. Gamba, and Anderson M. Winkler
Imaging local genetic influences on cortical folding, Aaron F. Alexander-Bloch, Armin Raznahan, Simon N. Vandeker, Jakob Seidlitz, Zhixin Lu, Samuel R. Matthias, Emma Knowles, Josephine Mollon, Amanda Rodrigue, Joanne E. Curran, Harald H. H. Goring, Peter T. Fox, and John Blangero
